Ann O'Rexia suffers from anorexia nervosa. In addition to a low body weight, decreased muscle mass, glycogen, and fat stores, she has iron deficiency anemia. She constantly feels weak and tired. When she walks, she feels pain in her calf muscles. On this visit to her nutritionist, they discuss the vitamin content of her diet and its role in energy metabolism. She is deficient in thiamine, riboflavin, biotin and niacin (the vitamin precursor of NAD+). In the context of the metabolic pathways discussed in Chapter 14, specifically how would these affect carbohydrate metabolism.
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Compare and contrast the three types of coronaviruses: "SARS-Cov, MERS-Cov and Covid-2019" in regards to their replication cycle, transmission, R0
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Explain why no organelles, such as a nucleus, are seen in the Anabaena. (Please type it out)
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1. One of the symptoms of COVID-19 is a loss of smell or
taste.
Identify the type and location of receptors that are likely to
be affected by the virus to cause a loss in smell/taste. Explain
why people have trouble tasting foods when they are congested due
to a cold or allergies.
2. How/why can smells evoke memories so strongly? Identify 1-2 smells that are your most and least favorite and explain why.
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longitudinal survey.
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Work from the Brown and Goldstein lab provided
insights into cholesterol homeostasis that were used to develop
several of the LDL cholesterol-lowering therapies, including
statins that remain in use today. However, in some patients,
statins were not as effective as expected, suggestive of additional
mechanisms regulating the LDL receptor. Investigate other LDL
cholesterol-lowering therapies (other than PCSK-9 inhibitors),
select 1, and compare and contrast the mechanisms of action between
the class of drug you select and statins. Include side effects for
both types of drugs and information on their efficacy.
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1)
IND’s are typically needed for the following: (more than one answer)
Group of answer choices
Human testing of a Monograph drug active in a new formulation using dose levels/concentrations approved in the Monograph.
Human testing of a Monograph drug active at a higher dose than that approved in the Monograph.
Human testing a Monograph drug active using a route of administration other than that approved in the Monograph
Human testing of a new chemical entity
2)
To grant a patent, the technology must be non-obvious and have utility. (True or False)
Group of answer choices
True
False
3)
Rectally administered suppositories can be used to avoid hepatic first-pass metabolism of systemically absorbed drug actives and this is their primary use in OTC drug products. (True or False)
Group of answer choices
True
False
4)
Which section(s) of the GI tract do NOT have villi present to increase absorptive surface area? (More than one answer)
Group of answer choices
Ileum
Descending colon
Esophagus
Jejunum
Cecum
5)
Under the FD&C Act, which of these shows that a lipstick is adulterated? (More than one answer)
Group of answer choices
Contains poisonous substances which might be injurious to user under the condition of use prescribed in the label
Contains a label that with listing of all ingredients
Contains a stand of stray hair inside the lipstick bullet
Contains small beads of liquid knowns as “sweating” around the lipstick bullet
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Do morphogens support a preformation or epigenetic view of development? Provide an example to support your answer.
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Why does a particular codon represent only one specific amino acid?
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Define the term symbiosis specifically as it applies in a biological context. Compare and contrast parasitism, mutualism, and commensalism using a specific example of each type of symbiosis. For all three examples, explain how each organism in the relationship is affected.
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QUESTION 4
Discuss the sanctity of life versus the quality of life debate as presented by Peter Singer. Your answer should demonstrate a solid awareness of the information presented in the text. Be as clear and specific as you can.
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1)The histone proteins of nucelosomes are often abnormally modified in cancer cells, leading to _____. a. an alteration in chromatin structure b. an alteration in levels of transcription c. double-stranded breaks in DNA d. All of the above e. Both a and b
2)
A DNA strand contains the sequence TCGGATGCACCT. A mutation happened that results in the sequence TCCGGATGCACCT. What type of mutation does this change represent?
|
a point mutation |
||
|
a missense mutation |
||
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frameshift mutation |
||
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a silent mutation |
3)
Chromosomal rearrangements might position a gene near heterochromatin. The gene's transcription
|
may be inverted. |
||
|
may be amplified. |
||
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may cease. |
||
|
will turn on. |
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Question 4 Part A: If you were to extract your own DNA would you expect it to look different from your plant DNA extract? Why or why not?
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