1)
IND’s are typically needed for the following: (more than one answer)
Group of answer choices
Human testing of a Monograph drug active in a new formulation using dose levels/concentrations approved in the Monograph.
Human testing of a Monograph drug active at a higher dose than that approved in the Monograph.
Human testing a Monograph drug active using a route of administration other than that approved in the Monograph
Human testing of a new chemical entity
2)
To grant a patent, the technology must be non-obvious and have utility. (True or False)
Group of answer choices
True
False
3)
Rectally administered suppositories can be used to avoid hepatic first-pass metabolism of systemically absorbed drug actives and this is their primary use in OTC drug products. (True or False)
Group of answer choices
True
False
4)
Which section(s) of the GI tract do NOT have villi present to increase absorptive surface area? (More than one answer)
Group of answer choices
Ileum
Descending colon
Esophagus
Jejunum
Cecum
5)
Under the FD&C Act, which of these shows that a lipstick is adulterated? (More than one answer)
Group of answer choices
Contains poisonous substances which might be injurious to user under the condition of use prescribed in the label
Contains a label that with listing of all ingredients
Contains a stand of stray hair inside the lipstick bullet
Contains small beads of liquid knowns as “sweating” around the lipstick bullet
In: Biology
Do morphogens support a preformation or epigenetic view of development? Provide an example to support your answer.
In: Biology
Why does a particular codon represent only one specific amino acid?
In: Biology
In: Biology
Define the term symbiosis specifically as it applies in a biological context. Compare and contrast parasitism, mutualism, and commensalism using a specific example of each type of symbiosis. For all three examples, explain how each organism in the relationship is affected.
In: Biology
QUESTION 4
Discuss the sanctity of life versus the quality of life debate as presented by Peter Singer. Your answer should demonstrate a solid awareness of the information presented in the text. Be as clear and specific as you can.
In: Biology
1)The histone proteins of nucelosomes are often abnormally modified in cancer cells, leading to _____. a. an alteration in chromatin structure b. an alteration in levels of transcription c. double-stranded breaks in DNA d. All of the above e. Both a and b
2)
A DNA strand contains the sequence TCGGATGCACCT. A mutation happened that results in the sequence TCCGGATGCACCT. What type of mutation does this change represent?
|
a point mutation |
||
|
a missense mutation |
||
|
frameshift mutation |
||
|
a silent mutation |
3)
Chromosomal rearrangements might position a gene near heterochromatin. The gene's transcription
|
may be inverted. |
||
|
may be amplified. |
||
|
may cease. |
||
|
will turn on. |
In: Biology
Question 4 Part A: If you were to extract your own DNA would you expect it to look different from your plant DNA extract? Why or why not?
In: Biology
Nucleotides of DNA are joined by a ____________ to form polynucleotides whereas amino acids are joined by a ______________ to form polypeptides.
Group of answer choices
Phosphodiester linkage / hydrogen bond
Phosphodiester linkage / glycosidic bond
Peptide bond/ phosphodiester linkage
Hydrogen bond/ peptide bond
Phosphodiester linkage/ peptide bond
In: Biology
The adaptive immune system has two major effector arms: humoral and cell-mediated. Discuss the need for such separate systems from the standpoint of common pathogenic organisms and substances. What might you think are the "weak links" in these systems?
1. How have some disease-producing organisms exploited these?
2. Does this help explain why it is extremely difficult to generate effective vaccines for some organisms? Give an example and explain your reasoning.
In: Biology
In: Biology
Write an introduction about cutaneous mycoses.
In: Biology
Electrons bound by NADH from glycolysis, the CAC, and the Pyruvate Dehydrogenase Complex are transferred to the Electron Transport Complex (Complex 1, Complex 2, Complex 3 and Complex 4) a series of 4 protein complexes. What is the order the electrons will travel from protein complex to protein complex?
In: Biology
How is the coronavirus pandemic affecting wildlife? With fewer cars on the roads, and with parks and wildlife areas closed to the public for several weeks, the Stay-at-Home Order (shelter in place) likely affected some animal populations in urban areas.
describe two examples of how animals have been
affected.
Make sure to include the type of animal affected, and how they are
affected. If you have directly witnessed affected wildlife, you may
use that as one example.
In: Biology
Explain what evolutionary adaptations, in general, exist in hyperthermophilic bacteria in terms of their cell membranes and cellular proteins. Your answer should explain how such adaptations provide advantages in terms of protein and membrane function at extremely high temperatures.
In: Biology