Question

In: Biology

The isotypes of immunoglobulin heavy-chains ______________________________. (Select all that apply.) A. are determined by the heavy-chain...

The isotypes of immunoglobulin heavy-chains ______________________________. (Select all that apply.)

A. are determined by the heavy-chain C and V regions


B. are gamma (γ), alpha (α), mu (μ), epsilon (ε), and delta (δ)

C. include κ and λ

D. carry out different functions in the immune response

Solutions

Expert Solution

B. Are gamma, alpha, mu ,epsilon and delta

D   Carry out different functions in the immune response.

Explanation:

There are five heavy chain isotypes these are – alpha, gamma, mu, epsilon, and delta. Fc region is common in all antibodies and it interact with the immune system. The class of antibody defines by the Fc portion of heavy chain.

So the isotypes of immunoglobulin heavy-chains are determined by, the isotypes of immunoglobulin heavy-chains are gamma, alpha, mu, epsilon, and delta. the isotypes of immunoglobulin heavy-chains carry out different functions in the immune response.

       These two are correct option.

     On the other hand lamda and k are the two types of light chain. So this option is not correct.

Each heavy chain has two regions one is constant region( C) and the variable (V) regions.But the isotypes of immunoglobulin heavy chain is determined by variable region not constant region. So this option is also not correct.


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