Several of our readings in past weeks have been on the effects on health of a microbiota shift. One example is the study of malnourished Malawian twins who had developed kwashiorkor. Can Koch's postulates be extended to cover a community of microbes? Explain which of Koch's postulates were fulfilled and which were violated in this study. What experiment(s) did the scientists do to fulfill Koch's third postulate?

reference link: http://science.sciencemag.org/content/339/6119/548.full?sid=69b84ea1-59af-41bb-bd62-2ba7388ce195

Real time PCR: how is it analyzed? what can be done to improve real time PCR? How do you know if the bullfight was good or not? What does it mean if the real time parameters are high, low, or if there were faults in something in the process seeing the results? Abound in your response.

Real time pcr:
• How to do?
• How it is interpreted?
• How it is optimized

Discuss how the use/purpose of horses has changed over time and describe how the horse industry differs from the various livestock production animals we've discussed this term. Discuss the structure of the horse industry. Compare and contrast it with the other animal industries discussed thus far.

Propose three hypotheses to explain why sexual reproduction has evolved. (At least 20 have been suggested!)

What are examples of technology that have extended out senses? What does it do? Advantages and Disadvantages? Give 2 examples.

Secretase family of enzymes are central to the processing of amyloid precursor proteins (APP) associated with the development of Alzheimer's disease. They have garnered much attention over the years as a possible therapeutic target for the disease. Would targeting these enzymes for inhibition be an effective strategy for preventing the onset of Alzheimer's related amyloid plaque formation. If not, can you think of another approach that might be effective that doesn't necessarily involve targeting these enzymes?

Article as reference https://drive.google.com/file/d/1yXnhMr8tRxgEtIGQPRAvZr69gAlHpwdj/view?usp=sharing

Please explain the following:

Understand the family of TGF beta signaling molecules (ligands).

Understand that the TGF beta superfamily of growth factor ligands are synthesized and secreted in an Inactive form, and need to be activated extracellularly by proteolytic cleavage.

Understand the structure of the bioactive form of TGF beta.

Understand the family of TGF beta receptor structure and function

1. Describe the steps in the immune response, beginning with an antigen entering the body and ending with activation of the various B- and T-cell types.

36) The majority of homeostatic processes in the human bodywork on the principle of positive feedback control (T / F)

37) Photosynthesis is not an example of an oxidation-reduction reaction

39) Which type of population age structure diagram is associated with low juvenile mortality and low reproductives rates?

40) Which organ system produces developmental hormones?

42) If one parent is heterozygous for a gene and the other parent is homozygous recessives for the same gene, what is the chance that they have a child showing the recessive form of the gene in their phenotype?