What do LDL receptor (LDLR) cytoplasmic domain mutations that cause familial hypercholesterolemia reveal about the receptor-mediated endocytosis (RME) pathway? Based on your knowledge of the entire endocytic process of LDL, are there other proteins in the pathway that if mutated might cause hypercholesterolemia? Explain how and why a mutation in a different protein in the pathway could cause disease. For a person who is homozygous for the NPXY mutation in their LDLR, can you think of a way to fix this individuals uptake of cholesterol?

for each generation, take 6 of the 10 alleles and give three to the deme on your left and three to the deme on your right. Conversely, add in three alleles from the deme on your left and three alleles from the deme on your right. Note that this requires that the entire class samples in unison.

Q8) How did the addition of gene flow affect genetic variation in your deme? Which model of gene flow (infinite island model or stepping stone) is most consistent with the pattern we simulated in class?

Why was Don Johanson's finding of the "First Family" so significant for resolving questions about Australopithecus afarensis?   

4. Together with a specific set of proteins, snoRNAs direct the meth- ylation or pseudouridylation of rRNAs. Does the snoRNA function as a scaffold, guide, ribozyme, blocker, decoy, and/or alterer of protein function or stability?

The following statement is FALSE.

Both eukaryotes and prokaryotes require a promoter region for gene translation.

(a) Identify the incorrect word(s).

(b) RE-WRITE the statement correctly.

i need help

During strenuous activity, the demand for ATP in muscle tissue is vastly increased. In rabbit leg muscle or turkey flight muscle, the ATP is produced almost exclusively by lactic acid fermentation. ATP is formed in the payoff phase of glycolysis by two reactions, promoted by phosphoglycerate kinase and pyruvate kinase. Suppose skeletal muscle were devoid of lactate dehydrogenase. Could it carry out strenuous physical activity; that is, could it generate ATP at a high rate by glycolysis? Explain.

Discuss the pros and cons of lactate production in active muscle. Why is lactate produced? What happens to the lactate?

The transformation of glucose to lactate in myocytes releases only about 7%
of the free energy released when glucose is completely oxidized to CO₂ and H₂O. Does this mean that anaerobic glycolysis in muscle is a wasteful use of glucose?

Question 6:

Calculate the genotypic frequencies that you would expect if the population is in Hardy-Weinberg equilibrium.

(Remember, that we are preparing to use the Chi-square goodness-of-fit test to determine if this population is in fact in Hardy-Weinberg equilibrium).

Round your answer to three decimal places and submit your answer in the correct format (e.g. 0.062).

(a) The frequency of the SS genotype is:

(b) The frequency of the Ss genotype is:

(c) The frequency of the ss genotype is:

The total number of leopards in this population is 284.

For reference:

S = dominant allele for brown pigmentation

s = recessive allele for red pigmentation (erythrism)

the frequency of the S (dominant) allele in this population: 0.916

the frequency of the s (recessive) allele in this population: 0.084

look into these supplements to see if they are causing/contributing to psychiatric symptoms. Provide a source or reference

- catecostim

- Brain-E DHA

-Neuro O2

-Acetyl-CH

-Ultrabiotics

which spinal nerve innervates the main important muscle for our respiration, and to which plexus of the peripheral nervios system does it belong to?

How is messenger RNA made and processed to mature RNA. List all the steps

Why is the coagulase test important in diagnosing infections with Staphylococcus? How does

the production of coagulase benefit a species of Staphylococcus in causing an

infection?

1. Which of the following observations would support part of the energy-diversity hypothesis?
   1. The total number of plants per site (not plants per species) is higher in sites with high actual evapotranspiration (AET).
   2. The total number of plants per site (not plants per species) is lower in sites with high actual evapotranspiration (AET).

Match the following terms with their correct definition:

1.__ adventitious                          A. This is the general term used for plant tissues that have the ability to perform mitosis for plant growth.

2.__ elongation                            B. This is the layer of cells in the root where you would expect to find the casparian strip.

3.__ phosphorus                          C. This is the term used to describe the route of water uptake by roots through the cortical cell plasmodesmata.

4.__ xylem                                  D. This term is used to identify the oldest xylem tissue found near the center of stem of dicot tree.

5.__ CAM                                   E. This is a tissue that is a component of vascular tissue produced by the vascular cambium in dicot plants.

6.__ endodermis                          F_(AB) This is the term used for the prop roots produced by corn and the pneumatophores produced by mangrove trees.

7.__ tuber                                  G_(AC) This term is used to identify the region of a root tip that is responsible for the primary increase in length during root growth.

8.__ flaccid                                 H_(AD) This the general term for the primary conductive (transport) cells of the phloem vascular tissue of the plant.

9.__ mycorrhizae                         I_(AE) These are fungi that are associated with plant roots and contribute to nutrient uptake by roots.

10.__ meristems                          J_(BC) This term is used to identify the secondary xylem found in the stem of monocot trees when they produce wood.

11.__ trichomes                           K_(BD) One of the key macronutrients required for proper plants growth and function.

12.__ symplastic                          L_(BE) This is the term used for a modified stem used for the storage of photosynthetic products in a potato plant.

13.__ heartwood                          M_(CD) This is the descriptive term for a plant cell that has experienced a net extracellular osmosis over a period of time

14.__ sieve cells                           N_(CE) Modified form of carbon fixation that allows desert plants to avoid the worst effects of photorespiration.

                                                O_(DE) These are outgrowths of leaf epidermal cells and a able to reduce air flow and water loss from leaves.

Which stage of cellular respiration produces the most ATP? Explain.

Explain why skeletal muscle is voluntary and cardiac muscle and smooth muscle are involuntary