BJ. is a 5-year-old boy who has suffered from repeated upper respiratory infections since he was 16 months old. At 4 years of age, he was diagnosed with allergic asthma. The following winter, at age 5, he was admitted to the hospital twice for acute asthma with a secondary bacterial pulmonary infection.
At the second admission, a complete blood count, sputum culture, and immune status work-up were ordered.
Laboratory Data
Assay Patient Results Reference Range
Hemoglobin 13.5 g/dL 11.5-14.5 g/dL
Hematocrit 40% 33-43%
Total WBC count 16.2 x 109/L 4-12 x 109/L
Lymphocyte Count 4.3 x 109/L 2.7-5.4
T lymphocytes 2.4 x 109/L 2.7-5.3
B lymphocytes 1.0 x 109/L 0.6-1.4
1. What is the etiology of this patient’s recurring infections? Explain your answer.
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