Question

Parkinson's Disease is a pathology associated with the:

A. Basal (Ganglia) Nuclei
B. Medulla oblongata
C. Cerebellum
D. Cerebral cortex
E. Limbic System

Answer 1

Answer - (A) Basal Ganglia Nuclei

Parkinson is the disease associated with the degeneration of the nerve cells which mainly affects the basal ganglia part of the brain which is also known as substantia nigra.

It occurs due to the dopamine imbalance and have some specific symptoms like in this peoples suffers from shaking stiffness and they face difficulty in walking talking and coordination etc.

This disease shows a common prevelance seen equally in both men and females and majorly seen after the age of 50 or 60 , this disease occurs due to the damage of neurons in the brain so this is called degenerative disorder .

This neurons normally secrete a chemical substance called dopamine and this is useful in coordination balance activity but due to the damage of the these neurons the dopamine secretion becomes less and patient suffers this disorder.

It is also seen that patient of parkinson disease also suffers from the deficiency of chemical noreoinephrine which is helpful in maintaning blood pressure and some major sympathetic functions.

In this there are few specific symptoms are seen like the tremors in the body , disturbed movement and coordination , slowness of the body etc.

This disorder is majorly brain affecting and dopamine restoration is important as a treatment ,

while from options we choose basal ganglia because neurons whom secrete the dopamine in the body are present here and due to the destroy of these neurons affects the level of dopamine and causes the parkinsonism.

while others parts of brain are involved in different functions of body.

In which limbic system is a different region of subcortical area and concerned with the detection and regulation of memory emotions fear arousal etc.

while some are part of CNS which regulates the other functions like learning memory etc which is cerebral cortex etc.

So these parts are not concerned with dopamine secretion.