An otherwise healthy 30 year old male is being observed in the Emergency Department for chest discomfort. Blood pressure is 140/95 mmHg, respiration rate of 24/minute. Temp 98.9 F. By cardiac monitor, heart rhythm is normal, with normal intervals. A normal QRS complex follows each P wave. A 6 second rhythm strip shows 8 QRS complexes. An ECG is normal. On echocardiogram, all cardiac chambers and heart valves are normal in appearance. Left ventricular end diastolic volume is 100 ml. Left ventricular end systolic volume is 40 ml. All calculations and units must be included in calculations for full credit.  Calculate heart rate. __________________________  Calculate stroke volume. __________________________  Calculate left ventricular ejection fraction. __________________________  Calculate cardiac output. __________________________  Calculate mean arterial pressure. _______________________

A patient appears to have “white coat” hypertension- very high blood pressure when they come to the doctor’s office. When they are relaxed at home, blood pressure is fairly normal. Blood tests show that the patient has high sodium levels and low potassium levels during these periods of hypertension. Additionally, the patient’s medical records also showed that blood pressure rises unusually during fasting and illness as well, and that they had to stop taking an anti-inflammatory drug due to hypertension as a side effect. The physician talks to a colleague who is an endocrinologist specializing in genetics (to the rescue!).

The endocrinologist concluded that the patient might have inherited a mutation that affects the activity of a steroid hormone receptor (Receptor A) that binds to a steroid hormone (Hormone A) that plays an important role in blood pressure regulation. She found that the patient has a mutation that allows Receptor A to be activated even better by a second, related steroid Hormone B. Hormone B can now, by accident, strongly activate Receptor A even within the normal range of blood levels regulated by its negative feedback loop.

• Hormone A: What is Hormone A? What regulates its secretion? What cells secrete it? What is its normal physiological role?
• Hormone B: What is Hormone B? What regulates its secretion? What cells secrete it? What is its normal physiological role?

Which environment separated by the respiratory membrane would display the highest oxygen partial pressure?

A)Pulmonary capillary blood

B) Alveolar air

PLEASE EXPLAIN

The Renin-Angiotensin-Aldosterone Pathway and the roles that the kidney plays in the human body and how it works to keep the body in balance. Include what happens if there is a homeostatic imbalance as it plays this role.

1. How does the heart rate from the subject at rest, immediately after exercise, and at 1 min, and 2 min after exercise compare? Explain the physiology reasons for any differences.

2.What is occurring during the P-Q interval? How do the average P-Q intervals from rest and each time interval compare? How does the average at rest value compare to the "normal" value?

3. How does the average pulse-wave amplitude from rest and each time interval compare? Explain any variations.

This discussion board will give you the opportunity to demonstrate your understanding of one function of the integumentary system and how it interacts with other body systems to contribute to homeostasis for the organism. Think about the functions of the integumentary system. Along with the barrier function of the skin, there are many other important functions that the integumentary system contributes to. Injury or pathology to the integumentary system often causes a potential disruption to the ability of a person to maintain homeostatic conditions. You will pick two of the following conditions and provide the following for each: the layers and structures of the integumentary system that are involved, the integumentary system functions that are lost or inhibited, and the compensatory steps that the body will take to overcome the deficit. It is fully expected that you will have to do some independent research to provide a robust response to this prompt - it would be in your best interest to start this assignment early!

Choose two of the following conditions to discuss:

Decubitis ulcers (i.e. bedsores)

Shingles

Second degree burn covering the majority of the thorax

Necrotizing fasciitis

Hyperhidrosis

what is the relationship between increased fat metabolism and hyperglycemia

Shoe size > 9

Pair Case Control
1      Yes     No
2       No    No
3       No       Yes
4      Yes      Yes
5       No       Yes

1. Compute the proper measure of association.
2. Interpret your results.
3. If you were to investigate a rare cancer in Lynchburg, where might you look for data?
4. What would be necessary legally and ethically to be able to utilize this data set(s)?

what are the different stages of follicle development in the ovary and what happens in each

Identify and provide a function of the structural components of a bone.

Explain the steps of hemostasis and the coagulation cascade

Carbohydrate digestion begins when the complex carbohydrate starch is broken down into maltose. Which enzymes catalyze the breakdown of maltose into monosaccharides, and where are the enzymes found?

a)Carbohydrases located throughout the intestines

b)Pancreatic amylase released by the pancreas

c)GLUT2 located on the basolateral surface

d)Disaccharidases located at the intestinal brush border

Size of cord segments:

1. The more superior, the more white matter. why is this?

2. grey matter is larger in cervical and lumbar regions. why is this?

Mrs. Smith was diagnosed with Stage IV breast cancer 15 months ago. She underwent
chemotherapy for several months before a bilateral mastectomy was performed. She then
completed six weeks of radiation therapy to the chest wall. Recently, she has been experiencing
the inability to manipulate the tongue during chewing and swallowing, as well as difficulty in
speech. Further investigation indicated that the left side of her tongue appeared to be paralyzed
when asked to protrude her tongue past her lips. An MRI was performed and revealed a lesion
present at the base of the skull that was affecting this particular cranial nerve.

question:

5.   Based upon your knowledge of the action of the nerve in Case Study 5, describe how proper functioning of this nerve is necessary for vocalization, food manipulation and swallowing.