Why is the mitochondria, ribosomes, and cell membrane less important than the nucleus overall? Are these cells all related to the nucleus.

We presume the following; It is understood that a new chemical material that is synthesized is possibly used in Corona Virus (Covid-19) treatment, for its experimentation in living organisms (in-vivo) to be done, tablets of this material must be made.

Explain and show information about all the pre-formulation studies and research that has to be performed for this formulation to be made.

In other words, a new substance is being made to be used as a cure for Covid19, in order for it to be used in living beings/ in-vivo testing, we need to have this substance made into a tablet form so that it can be ingested.

In order to make these tablets, there are formulation procedures and pre-formulation procedures, What are the stages and procedures that are made in the pre-formulation stage of the formation of this tablet?

How to ensure the label from heavy and light protein was 100% effective? How do you verify the proteins are 100%?

(please do assignment )

topic : Structure, Function of
Covid-19 and
inhibition by
designed medicines
Research proposal must be contained
1. Abstract
2. Introduction
3. Structure
4. Function
5. Treatment
6. Referencs ( should be according to
(Pakistan journal of Botany Format))

In eukaryotes: what is the difference between the regulation of general versus specific translation? Describe one regulatory mechanism per each type.

1- The best time to collect plant specimens to analyze the biodiversity of an area is

a.   any time
b.   once, at the beginning of the growing season
c.   at two or three times during the entire growing season
d.   once, at the end of the growing season

2-Vascular tissue is composed of cells

a.   specialized in transporting water and other substances throughout the plant
b.   that pump fluids from one area to another
c.   responsible for ensuring water does not cross cell membranes
d.   both a and b

3-

A cell type in the phloem that lacks nuclei, mitochondria, or vacuoles, and has large pores through the cells walls at either end, is called a

a.   xylem   c.   sieve-tube element
b.   sieve tube   d.   companion cell

14. What is the general purpose of feedback inhibition? What is the problem if feedback inhibition happens when it isn’t supposed to? 15. How do the effects of insulin resistance compound to decrease cellular responses to insulin? 16. Hypothesize a mechanism by which the GLUT4 transporter’s fusion to the cell membrane could be decreased.

Topic : The mechanism of DNA repair (write a review on it more than 3000 words)

1. The final concentration of dNTPs in a PCR should be 1 mM. You currently have each nucleotide as separate 10 mM stocks. How would you made up 400 µl of a dNTP mix?
2. You are given a 8 mM solution of a protein (MW 27,000 g/mol). Using this information fill in the blanks below to fit the units given.

1. ____________________μmole/ml
2. ___________________ g/L
3. ___________________ mg/ml

3. You order a 19-mer oligonucleotide for a PCR reaction. The molecular weight is 5858.9 and the amount you receive is 36.7µg. You need to make up a 5µM solution. What volume of water do you dissolve your oligo in?
4. You lypholize 1ml of a 20nM solution of a 50kDa protein dissolved in water. What is the expected weight of the dried protein?
5. If the average molecular mass of an amino acid is 110Da, what would the estimated molecular weight of a 33-mer peptide be? (in kDa)

The melting temperature for phospholipid membranes is strongly impacted by fatty acid composition and cholesterol contain. You have 3 different membranes. Membrane 1 is formed by phosphoglycerides with 2 chains of behenate

membrane 2 is formed by phosphoglycerides with 2 chains of stearate and membrane 3 is formed by phosphoglycerided with 2 chains of myristate. The structural properties of fatty acids are summarized in Table below. Which membrane (1, 2 or 3) has the lowest melting temperature and which membrane has the highest melting temperature. Explain your reasoning.

1.Describe the followings:
A. The 2 types of immunosuppression?
B. which part of the immune system is responsible for rejection in organ transplant?
C. why does tissue damage occurs in acute rejection after organ transplantation?
2. MHC System
2.1 What is MHC polymorphism?
2.2 Why is it so important?
2.3 Why MHC is called HLA?
2.4 What are the function of MHC I and MHC II?
3. How to B and T cells differ with respect to antigens that they bind?

The interactions between pathogens and their mammalian hosts are played out on co-evolutionary battlegrounds. Discuss this statement by explaining:
a) Why humans are constantly susceptible to infection despite the evolution of complex innate and adaptive immune responses and,
b) How pathogens, and the molecules they produce, interact with macrophages to cause disease and can sometimes be exploited for therapeutic benefit.

You are studying myosin V, a class of myosin which can be used in cells to transport vesicles by “walking” along actin filaments, towards the plus ends of these filaments. You have identified a mutation in the gene for myosin V that affects its ATP binding site. This mutant myosin V (M) can still perform the entire cross-bridge cycle, but it takes much longer to hydrolyze ATP compared to a wild type myosin V (W).

a) Would the duration of the cross-bridge cycle be longer in M or W?Explain?

b) Would the duty cycle (the proportion of the cross-bridge cycle in which myosin is bound to actin) be longer in M or W?Explain?

c) How would this difference in duty cycle affect the ability of M to transport a vesicle along an actin filament? Explain.

In comparing Drosophila and human genomes, which of the following statements is correct?

A The amount to total DNA in genome is similar.

B The number of identified protein motifs is similar.

C The average size of introns is similar.

DThe amount of non-coding DNA is similar.

E The number of introns per gene is similar.