Questions
Describe how/where protein digestion occurs in the body and how zymogenic serine proteases contribute to the...

Describe how/where protein digestion occurs in the body and how zymogenic serine proteases contribute to the process.

In: Biology

After researching neurotensin , decide which part of that peptide pathway to target so a  drug will...

After researching neurotensin , decide which part of that peptide pathway to target so a  drug will enhance learning and memory.

a) Which part of the peptide pathway will you target?

b) How will your drug affect that target? Remember to use your core pharmacology concepts to help you decide this.

4) Prepare a 1 page poster (A3 size) advertising your new drug. Your poster must include the following required elements:

a) The name of your new drug (be creative!).

b) A brief description of the peptide pathway your drug acts on, and how this peptide affects learning and memory.

c) An explanation of the mechanism of action for your drug. Use a flow diagram to help explain this.

d) A catchy marketing slogan to advertise your drug. (For the purposes of this exercise, we will disregard the normal regulations that govern the marketing of pharmaceuticals in Australia!).

e) Reference information. You can choose your preferred referencing style, and where you place this information on your poster (although it must be on the same page as the poster, not on the back). There is no minimum number of references.

In: Biology

Explain how smoking alters the anatomy and physiology of the respiratory tract and leads to emphysema.

Explain how smoking alters the anatomy and physiology of the respiratory tract and leads to emphysema.

In: Biology

Given: bicoid genes are maternal genes; kruppel genes are gap genes, even-skipped genes are pair rule...

Given: bicoid genes are maternal genes; kruppel genes are gap genes, even-skipped genes are pair rule genes, gooseberry genes are gooseberry. Predict the effect of scenarios below on expression levels of each of these gene classes in the embryo described (will expression increase, decrease, or be unaffected?) and explain the reason for your prediction.
a. a fly embryo has a mutation that blocks expression of the kruppel gene


b. a fly embryo has a mutation that blocks expression of the bicoid gene.

c. a fly embryo has a mutation that increases expression of the even skipped gene.

In: Biology

For this week's discussion, choose an animal that you find interesting, and report one adaptation that...

For this week's discussion, choose an animal that you find interesting, and report one adaptation that it possesses. Be sure to report the environmental condition that the adaptation helps the animal to overcome and the references you used to locate the information.

In: Biology

Experiment 1: Neutralization of Acids and Bases Data Tables and Post-Lab Assessment Container Chemical Contents Litmus...

Experiment 1: Neutralization of Acids and Bases

Data Tables and Post-Lab Assessment

Container

Chemical Contents

Litmus Results

Additional Observations

A

B

C

Table 2: Initial Litmus Test Results

Table 3: Neutralization

Amount of Acid

Litmus Result

1 mL

2 mL

3 mL

4 mL

5 mL

Post-Lab Questions

State your hypothesis (developed in Step 8) here. Be sure to include what you think the pH will be, and why.

What is a neutralization reaction?

When might neutralization reactions be used in a laboratory setting?

At what point was the solution in beaker “B” neutralized?

What do you think would have been the results if a stronger solution of sodium bicarbonate was used? Would it take more or less to neutralize? What about a weaker concentration of sodium bicarbonate?   

In: Biology

Which of the following is arguably the world's first true microbiologist? Van Leeuwenhoek. Robert Koch. Rudolph...

Which of the following is arguably the world's first true microbiologist?

Van Leeuwenhoek.

Robert Koch.

Rudolph Virchow.

George Washington.

Louis Pasteur.

In: Biology

For this discussion post, you will need to write an original post of at least 450...

For this discussion post, you will need to write an original post of at least 450 words. Then respond to at least two peers by Saturday.

Nearly everyone knows someone with type 2 diabetes. It may be your grandfather, mother, professor, or even the young person sitting next to you. Those with type 2 diabetes often do not talk about it and may not even realize they have it. Type 2 diabetes mellitus is rapidly increasing in the United States in parallel with the increase in levels of obesity. Those with a family history are especially prone to developing the disease. Over 30 million peo­ple in the United States are living with type 2 diabetes and the medical care and social costs are estimated at over $300 billion dollars a year. It is predicted that by 2025 there will be over 50 million people with type 2 diabetes costing the country over $500 billion if cur­rent trends continue. Type 2 diabetes is a progressive disease which affects blood vessels and nerves and thereby impacts nearly every organ in the body. The impact on the feet from neuropathy and diminished blood supply may lead to infections and amputations. The impact on the retina can lead to blindness while the impact on the kidneys is among the leading cause of renal fail­ure requiring expensive hemodialysis or transplanta­tion. The impact on the blood vessels also increases the probability of coronary artery disease and stroke. Most recently an increased risk of dementia has been recognized. Thus, type 2 diabetes ranks at the very top of the conditions classified as a 21st-century epidemic. Testing for diabetes is increasingly being done as part of routine health care using the hemoglobin Ale blood test which measures average blood sugar con­trol over a 2-month period. Many of the newly recog­nized diabetics have mild disease that would greatly benefit from weight loss. Weight loss has been the approach to preventing and controlling type 2 diabetes for many years. Even loss of 5% of body weight can have a substantial impact on blood sugars. Approaches to weight loss include a variety of partially successful diets most of which can reduce weight in the short run, but all of which are diffi­cult for individuals to maintain in the longer run. Gas­tric bypass surgery, despite its costs and potential side effects, has been shown to have an immediate effect on type 2 diabetes even before the impacts of weight loss occur. It is now often recommended for those with type 2 diabetes and a BMI of greater than 35. Management of most patients with type 2 diabe­tes requires the efforts of several types of clinicians. A primary care clinician, and increasingly a nurse practitioner or physician assistant, is often key. Other health professionals who are needed for high quality preventive care may include nutritionists to work with patients on their eating habits, podiatrists to prevent and treat foot problems, as well as optometrists and ophthalmologists to identify and treat diabetic eye problems to prevent blindness. Type 2 diabetes is often cited as a disease which requires shared decision-making and self-care. Ifinsulin is required for management of the disease, adjustment to prevent high and low blood sugars often rests on the knowledge and engagement of patients and families. Type 2 diabetes can be a very expensive disease to treat especially when hospitalization is required for very high blood sugar or for complications of the disease. Treatment of high blood pressure among type 2 diabetics has been shown to reduce costs as have annual influenza vaccinations. Early identifica­tion of damage to the retina from type 2 diabetes and laser treatment has been shown to be an effective and low cost approach to preventing blindness. Studies of the underlying mechanism for the development and progression of diabetes may in the future lead to better methods for prevention and treat­ment. An increasing number of treatments for type 2 diabetes have been approved by the U.S. FDA. It is not yet clear which treatments work best and for whom they are most effective. Comparative effectiveness research is now under way to help clinicians tailor the available treatments to the individual patient.

1. Identify interventions discussed in this case which can be classified as primary, secondary, and tertiary. Explain.
2. Identify ways that this case suggests that coordi­nation of health care can improve the quality of care for type 2 diabetics. Explain.
3. Identify ways that this case suggests that the cost of care for type 2 diabetes can be reduced while increasing or maintaining quality. Explain.
4. What role should society at large play in reduc­ing the epidemic of obesity? How should it be accomplished?
5. How would you suggest combining the approaches to type 2 diabetes discussed in this case to prevent and treat type 2 diabetes?Explain.

In: Biology

Determine which of the following observations are testable. For those that are testable: Determine if the...

Determine which of the following observations are testable. For those that are testable: Determine if the observation is qualitative or quantitative Write a hypothesis and null hypothesis What would be your experimental approach? What are the dependent and independent variables? What are your controls - both positive and negative? How will you collect your data? How will you present your data (charts, graphs, types)? How will you analyze your data? Observations 1. A plant grows three inches faster per day when placed on a window sill than it does when placed on a on a coffee table in the middle of the living room. 2. The teller at the bank with brown hair and brown eyes is taller than the other tellers. 3. When Sally eats healthy foods and exercises regularly, her blood pressure is 10 points lower than when she does not exercise and eats fatty foods. 4. The Italian restaurant across the street closes at 9 pm but the one two blocks away closes at 10 pm. 5. For the past two days, the clouds have come out at 3 pm and it has started raining at 3:15 pm. 6. George did not sleep at all the night following the start of daylight savings.

In: Biology

Biology Ecology Unit 1. A.) Describe how the phenomenon of bioaccumulation occurs in an ecosystem. What...

Biology Ecology Unit

1.

A.) Describe how the phenomenon of bioaccumulation occurs in an ecosystem. What chemical/physical properties make a compound bioaccumulate? Which organisms are affected the most and why?

B.) Which scientist is first credited for bringing this phenomenon to light, what book did she write? Briefly explain the reaction and ultimate outcomes that resulted.

2. Explain how the wildlife values of different seral (successional) stages change during the process of succession in the lowland forests of Western Washington in terms of forage, browse and cover.   Be sure to describe how this relates to the diversity and structural complexity of these stages.

In: Biology

Exercise 7: Experimental Variables Determine the variables tested in the each of the following experiments. If...

Exercise 7: Experimental Variables Determine the variables tested in the each of the following experiments. If applicable, determine and identify any positive or negative controls. Observations 1. A study is being done to test the effects of habitat space on the size of fish populations. Different sized aquariums are set up with six goldfish in each one. Over a period of six months, the fish are fed the same type and amount of food. The aquariums are equally maintained and cleaned throughout the experiment. The temperature of the water is kept constant. At the end of the experiment the number of surviving fish is surveyed. A. Independent Variable: B. Dependent Variable: C. Controlled Variables/Constants: D. Experimental Controls/Control Groups: 2. To determine if the type of agar affects bacterial growth, a scientist cultures E. coli on four different types of agar. Five petri dishes are set up to collect results: ? One with nutrient agar and E. coli ? One with mannitol-salt agar and E. coli ? One with MacConkey agar and E. coli ? One with LB agar and E. coli ? One with nutrient agar but NO E. coli All of the petri dishes received the same volume of agar, and were the same shape and size. During the experiment, the temperature at which the petri dishes were stored, and at the air quality remained the same. After one week the amount of bacterial growth was measured. A. Independent Variable: B. Dependent Variable: C. Controlled Variables/Constants: D. Experimental Controls/Control Groups:

In: Biology

NOTE : ESSAY QUESTION - PLEASE ANSWER IN DETAIL (1-2 paragraphs) Question : Discuss the characteristics,...

NOTE : ESSAY QUESTION - PLEASE ANSWER IN DETAIL (1-2 paragraphs)

Question : Discuss the characteristics, inheritance, and development of cancer; specifically talk about the role of genes, gene regulation, and the environment in the development of cancer. In addition, make sure to talk about why it is so difficult to treat/cure cancer.

In: Biology

In words, trace blood flow through the systemic and pulmonary circuits.

In words, trace blood flow through the systemic and pulmonary circuits.

In: Biology

describe how healthy diet works to prevent cardiovascular disease, diabetes, obesity, and other health problems.

describe how healthy diet works to prevent cardiovascular disease, diabetes, obesity, and other health problems.

In: Biology

1. In what part of a hepatocyte would a drug interaction involving CYP enzymes most likely...

1. In what part of a hepatocyte would a drug interaction involving CYP enzymes most likely occur?

A. Endoplasmic reticulum

B. Lysosomes

C. Golgi apparatus

D.Outer cell membrane

E. Nucleus membrane

2. Simvastatin is at higher risk of initiating rhabdomyolysis when co-administered with all except the following?

A. Anti-IL-6 therapy (tocilizumab)

B. Strong CYP3A4 inhibitors

C. Grapefruit juice

D. Mechanism-based CYP3A4 inhibitors

E. Hepatocyte OATP inhibitors

In: Biology