Why is it important to randomly select your plots when sampling species diversity?

In a population of 16,000 people, 67 are affected with a mild autosomal recessive condition. What is the estimated number of carriers for this condition in this population?

Describe the molecular mechanisms of mitochondrial ATP synthesis

biochem

A couple have experienced multiple miscarriages, and a balanced translocation is suspected to be the cause. Which form of genetic testing would be most appropriate?

a. Microarray

b. Karyotype

c. Amniocentesis

d. Next-gen sequencing

Continuing from the last question, who should be tested first? a. The man b. The woman c. Neither partner takes priority

Describe the β-oxidation of the fatty acid palmitate.

biochem question

Which of the following does not bind to Fc receptors? a. whole Ig b. fc c. heavy chain d. light chain

The enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.

The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9 mol/l). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7 mol/l).

Compute the total concentration of [D1]tot that is needed to bind 90% of the HIV-RT at the given concentration [E]tot.You do NOT have to consider competition betwwen the drugs D1 and D2! They are administered separately.

Compute the total concentration of [D2]tot that is needed to bind 90% of the HIV-RT at the given concentration [E]tot. You do NOT have to consider competition between the drugs D1 and D2! They are administered separately.

What is the order for monoclonal antibody production?

Growth of hybridoma cells
Plasma cells isolated from mouse spleen
Growth of plasma cells
Immunisation of mouse spleen
Growth of myeloma cells
Fusion of plasma cells and myeloma cells

The restriction endonuclease BamH1 has the recognition sequence G/GATCC and Sau3A the recognition sequence /GATC. Genomic DNA (G/C content = 56%) is digested with Sau3A and ligated into a vector digested with BamH1. What percentage of fragments could potentially be ligated into the vector and what is the average fragment length of the insert DNA?

Precursors of neural cells (neural tube) are able to separate from the precursors of epidermal cells because: a. All of the above b. Differential adhesion occurs c. E-cadherin expression is decreased in neural precursors d. N-cadherin expression is increased in neural precursors.

Cadherin adhesion proteins are described by the following, except?

How are autopolyploids different from allopolyploids? Describe one way autopolyploids can be formed and one way allopolyploids can be formed.