A couple have experienced multiple miscarriages, and a balanced translocation is suspected to be the cause....

A couple have experienced multiple miscarriages, and a balanced translocation is suspected to be the cause. Which form of genetic testing would be most appropriate?

a. Microarray

b. Karyotype

c. Amniocentesis

d. Next-gen sequencing

Continuing from the last question, who should be tested first? a. The man b. The woman c. Neither partner takes priority

Solutions

Expert Solution

SOLUTION- option B that is KARYOTYPE is right

when assessing a new patient with two or more spontaneous losses, it is important to obtain POC karyotype results from past losses, if available or to obtain the tissues form those losses for subsequent genetic analysis. this allows the practitioner to determine more precisely whether a diagnostic workup for is indicated prior aneuploid losses likely reflect the high baseline rate of aneuploidy noted in all spontaneous miscarriages.if the fetal karyotype of one or more of the reported losses is unknown. assuming euploidy may result in an unnecessary set of diagnostic tests in a patient who may not have experienced reported unexplained losses and would be unlikely to benefit from further diagnostic testing. a karyotype is a picture of a person's chromosome the packages of genetic material that exists within the nucleus of every cell in the body.in order to obtain a parental karyotype, blood that is usually white blood cells from one or both parents is used. doctors used the test only for couples with an increased risk of having a chromosome related conditions

so both should be tested but men's first

THANKS

gladiator answered 1 year ago

Next > < Previous

Related Solutions

at what stage of meiosis does translocation occur in order to cause Down syndrome

Discuss the cause of down syndrome (ex: insertion, deletion, inversion, translocation or whole chromosome issue), signs,...

Discuss the cause of down syndrome (ex: insertion, deletion, inversion, translocation or whole chromosome issue), signs, symptoms and degrees of the disease

Japan has been mired in a recession/depression for a couple of decades now, and has experienced...

Japan has been mired in a recession/depression for a couple of decades now, and has experienced very low inflation, and in some cases deflation. The Japanese Prime Minister (Abe), Chairman of the Bank of Japan (Kuroda), and others have desperately tried to induce inflation in the economy, thus far without success. Kuroda has been using what some call the “Peter Pan” strategy, where “Dreams do come true, if only we wish hard enough.” With that backdrop, what are “animal spirits”...

Which one of the following is not one of the Balanced Scorecard’s four generic perspectives? Multiple...

Which one of the following is not one of the Balanced Scorecard’s four generic perspectives? Multiple Choice financial internal business processes innovation and learning marketing and advertising

A sport utility vehicle design is suspected to have propensity for rollover. In a test, out...

A sport utility vehicle design is suspected to have propensity for rollover. In a test, out of 600 vehicles, 17 are observed to rollover. At a significance level of 0.05, test the hypothesis that proportion of vehicles with rollover problem is more than 2%. a. Write the appropriate hypothesis. b. Test the hypothesis using P-value approach, c. Test the hypothesis using z-test, and d. Test the hypothesis using Confidence Interval method. e. Clearly write your conclusion. f. If the true...

A sport utility vehicle design is suspected to have propensity for rollover. In a test, out...

A sport utility vehicle design is suspected to have propensity for rollover. In a test, out of 600 vehicles, 17 are observed to rollover. At a significance level of 0.05, test the hypothesis that proportion of vehicles with rollover problem is 2%. a. If the true fraction of defects is found to be 2.5%, find the type II error. b. What is the minimum sample size needed to detect type II error within 5% accuracy if the true fraction of...

Identify the item below that would cause the trial balance to not balance. Multiple Choice The...

Identify the item below that would cause the trial balance to not balance. Multiple Choice The cash payment of a $1,190 account payable was posted as a debit to Accounts Payable and a debit to Cash for $1,190. The purchase of office equipment for $2,300 was posted as a debit to Office Supplies and a credit to Cash for $2,300. The purchase of office supplies on account for $3,250 was erroneously recorded in the journal as $2,350 debit to Office...

Identify the item below that would cause the trial balance to not balance. Multiple Choice The...

Identify the item below that would cause the trial balance to not balance. Multiple Choice The purchase of office supplies on account for $3,250 was erroneously recorded in the journal as $2,350 debit to Office Supplies and $2,350 credit to Accounts Payable. A $1,000 collection of an account receivable was erroneously posted as a debit to Accounts Receivable and a credit to Cash. The purchase of office equipment for $1,200 was posted as a debit to Office Supplies and a...

multiple choice 1-The leading cause of death in PUBHland in 15 years is likely to be:...

multiple choice 1-The leading cause of death in PUBHland in 15 years is likely to be: Heart disease Road injuries Malaria 2-In 5 years, PUBHland will face increased rates of NCDs because: Fewer people will die of communicable diseases and risk factors for NCDs will have grown 80% of the population will be consuming tobacco The majority of PUBHland's population will be over 55 3- If present economic and social trends continue, how will the burden of disease in PUBHland...

for someone suspected to have covid syptoms, what clinical significant is relevant to respiratory assesment

Subjects