If the unknown sample was tested to have above normal levels of bilirubin (it tested to have high bilirubin levels), what other biochemistry tests should be performed? Justify your answers.

Sensory Systems

General Sensory

1. Stimuli in the environment are detected by ___________. _________ detect stimuli in the outside environment while ________ detect internal stimuli. ________ detect chemicals; ________ detect pressure; ________ detect photons; _________detect changes in shape; ________ detect changes in muscle length
2. Receptors can only detect stimuli that is presented in the ___________. Smaller/larger receptive field allow for better precision. Receptors generate ___________ which triggers __________ in sensory neurons. Sensory neurons relay information to the _________ then to the __________ where stimuli is perceived.

Taste

1. Taste receptors are ___________; they are located in _________. ________ trigger salty taste; ________ trigger sweet taste; ________ trigger bitter taste; _______ trigger umami taste; ______ trigger sour taste.
2. _________ and _______ chemicals directly enter taste cells to depolarize them. __________ chemicals bind to receptors which activate second messenger system.
3. Taste cells activate neuron is CN _________ which relay the information to the __________ and then to __________ then finally to the _________ where taste is perceived.

Smell

1. Olfactory receptors are located _____________. Binding of odorants to olfactory receptors activates _________ which activates ___________ enzyme which converts __________ to ________. cAMP opens ________ to _______ the olfactory neuron. The olfactory neurons synapse in the _________ and then to the _________ where odor is perceived.

Vision

1. __________ photoreceptors are used for bright light conditions and for seeing _______. ________ photoreceptors are used form dim light conditions. There are ______types of cones. Blue cones respond best to light of _____; Red cones respond best to light of ________; and green cones respond best to light of _________. Rods respond best to light of _______.
2. The part of the photoreceptor that responds to light is the __________ which is made of ________ and ________.
3. In the dark, cGMP opens _________ on the photoreceptors which allows ______ to enter. This is called the __________ which depolarizes the ________ which releases ________ to inhibit bipolar cells. As a result, bipolar cells can’t activate __________. As a result, no _________ is generated in the optic nerve.
4. In the light, photons of light strike to photopigments to convert ________ to _______. This change activates _________ which activates __________ which converts cGMP to ________. A decrease in cGMP decreases the _________ current. As a result, bipolar cells are no longer inhibited by _______. Bipolar cells then stimulate _________ which generate action potentials in the ________.
5. The scotopic system uses many _________ to activate fewer ________ which activate fewer _________. This is an example of __________. This system uses _________ to respond to low intensity light
6. The photopic system uses __________ to activate __________ to activate __________. Due to the lack of __________, this system is not suitable for __________ but it is ideal for _________.
7. Visual pathway
   1. Bipolar cells synapse with _______ in the retina which, in turn, synapse in the ________; third order neurons then terminate in the _________ where vision is perceived.
8. Vision abnormalities
   1. _________ is also called nearsightedness; in this condition image comes into focus _________
   2. _________ is also called farsightedness; in this condition, image comes into focus ________
   3. _________ is condition that prevents the image from coming into focus
   4. _________ is normal vision

Hearing

1. The pitch of a sound is based on its ________. The loudness of sound is based on its ________. Loudness is measure using a _________ scale. 20 db is ________ times louder than the hearing threshold.
2. The receptor for hearing is the _________ which is located in the _________. The receptor has ______ and _______ hair cells. The __________ are responsible for hearing and the _______ are responsible for cochlear tuning.
3. The ________ are activated when their stereocilia __________ and are inhibited when the stereocilia __________. Bending of the stereocilia towards the _______open ________ to allow _______ to enter the cells. This causes depolarization of the _______ which activates ________.
4. Pathway
   1. Auditory nerve synapse in the _________ and activate secondary neurons which project to the ________ to activate tertiary neurons which project to the ________ to activate quarternary neurons which project to the _________ to activate 5^th order neurons that terminate in the _______ where hearing is perceived.  
5. Hearing loss
   1. Damage to the ________ leads to sensorineural hearing loss whereas obstruction or damage to the ________ may lead to conduction hearing loss.

Equilbrium

1. _____________ detect angular movements of the head; the _________ detects vertical movements of the head; the ________ detects horizontal movements of the head.
2. The equilibrium structures (apparatus) contain ________ which are depolarized when _________. These cells then activate __________ which terminate in the _________. Neurons then project to the _________ and then to the ________.

. You have been hired as a food service manager in school cafeteria ,As food service manager and dietitian kindly explain how you supervise and fulfill following tasks.  (one paragraph )

a. How you will take Precaution for safe food production

b. How you will Evaluating menus for different age group children

c. write down any 4 factors you will keep in mind while designing menu for schools

Mr. and Mrs. John Takahama, a young couple who had been trying unsuccessfully to have a family for years, underwent a series of tests with a fertility clinic to try to determine the problem. Mr. Takahama was found to have a normal sperm count, and the sperm morphology and motility were normal. Mrs. Takahama's history sheet revealed that she had two episodes of PID during her early 20s, and the time span between successive menses ranged from 21 to 30 days. She claimed that her family was "badgering" her about not giving them grandchildren and that she was frequently despondent. A battery of hormonal tests was ordered, and Mrs. Takahama was asked to perform a cervical mucus test and daily basal temperature recordings. Additionally, gas was blown through her uterine tubes to determine their patency. Her tubes proved to be closed and she was determined to be anovulatory. (1) If Mr.Takahama count had been low, what type of information should be collected to determine the cause of the low count? (2) What do you suggest might have caused the closing of her tubes? Which of the tests done or ordered would have revealed her anovulatory condition? What is PID? What would cause this condition?

Sperm can survive in the female reproductive system for six days, but they need to have 10 hours after ejaculation to undergo capacitation. Ovulation typically occurs on day 14 of a woman's menstrual cycle. An ovulated egg can survive only up to 24 hours if it is not fertilized. Given this information, what days of a woman's sexual cycle would be a window of opportunity for an egg to be fertilized?

Mary, the director of nursing at a regional blood bank, is concerned about the declining number of blood donors. It’s May, and Mary knows that the approaching summer will mean increased demands for blood and decreased supplies, especially of rare blood types. She is excited, therefore, when a large corporation offers to host a series of blood drives at all of its locations, beginning at corporate headquarters. Soon after Mary and her staff arrive at the corporate site, Mary hears a disturbance. Apparently, a nurse named Peggy was drawing blood from a male donor with a very rare blood type when the donor fondled her breast. Peggy jumped back and began to cry. Joe, a male colleague, sprang to Peggy’s defense and told the donor to leave the premises. To Mary’s horror, the male donor was a senior manager with the corporation.

- What is the ethical dilemma in this case?

- What values are in conflict?

- How should Mary deal with Peggy, Joe, the donor, and representatives of the corporation?

Chapter 22

2. What is the relationship between stress and disease? If stress levels were high, how might age and personality type affect the risk of specific diseases?

3. What observations and clinical test results would indicate an individual was under stress?

4. How would you use psychophysiology to explain the Chinese rice powder test?

5. Compare and contrast psychological stress. What is the relationship between physiological stress and psychological stress?

Of the following answers, which correctly describes why herd immunity against SARS-CoV-2 would result in reduced transmission of the virus?

a.) the virus can infect individuals with immunity, but the immune system would ignore the virus, so no symptoms would occur

b.) the virus is unable to enter and infect individuals who have immunity

c.) individuals with immunity would have a rapid and effective humoral immune response against the virus which would prevent the virus from replicating and shedding

d.) individuals with immunity would have a stronger innate immune response against SARS-CoV-2 so macrophages would recognize and destroy the virus quicker

What is spermatogenesis? In what specific structure does this occur? What is oogenesis? What is another function of both the ovary and testis?

What is gluconeogenesis? What reactants are used? What is the product?

Discuss ALL of the steps involved in the excitation and contraction of a myofiber, in correct order. Start with the arrival of the first action potential at the axon terminal, and end with the active transport of Ca+2 into the SR. You may use outline/ bulleted list/ flow chart formats if you prefer.  

Daniel Purcel was diagnosed with type 1 diabetes mellitus when he was 12 years old. He is now a nursing student. He has managed to control his diabetes throughout school. However, when he began his clinicals, his regular schedule of meals and insulin injections was completely disrupted. One morning, Daniel completely forgot to take his insulin. At 7am he drank orange juice and ate two doughnuts. At 8am he drank more juice because he was very thirsty. He mentioned to a fellow student that he felt confused, weak, and that his heart was racing. At 9:06 am, he fell unconscious. He was transferred immediately to the emergency room, where the following information was obtained:

Blood pressure: 90/40
Pulse: 130, regular, strong
Respirations: 32, regular rhythm, deep, labored (“Kussmaul”) Plasma glucose: 560 mg/dL (normal fasting 70-110 mg/dL) Plasma HCO3-: 8 mEq/L (normal 24 mEq/L)
Plasma ketones: ++ (normal none)
Arterial PO2: 112 mmHg (normal 100 mmHg)
Arterial PCO2: 20 mmHg (normal 40 mmHg)
Arterial pH: 7.22

The physician determined that Daniel was in diabetic ketoacidosis. He was given an intravenous infusion of isotonic saline and insulin. Later, after his blood glucose had decreased to 175 mg/dL, glucose was added to the infusion. Daniel stayed in the hospital overnight. By the next morning, his blood glucose, electrolytes, and blood gas values were normal.

Questions:

18.Which acid-base disorder did Daniel have? What caused it? Why did he present with Kussmaul respirations? Explain these all in the context of the laboratory test results.

19.How did Daniel’s failure to take insulin cause this acid-base disorder?

20.Explain Daniel’s thirst, low blood pressure, tachycardia, confusion, and weakness.

21.Explain the basis for the treatments provided (saline, insulin, and glucose).

Which of the paleoenvironment hypotheses have been used to describe early hominin diversity, and which have been used to describe bipedalism?