Imagine conducting the following experiment. Take a sample of the native folded peptide and measure the amount of peptide required to inhibit the activity of a potassium channel, say the Kv4.2 channel, by 50%. We will call this value the IC₅₀ value. For our peptide, IC₅₀ = 5 nM for the Kv4.2 channel. Treat the peptide with a mixture of 2-mercaptoethanol and guanidine hydrochloride. Remove the 2-mercatoethanol and then the guanidine hydrochloride to allow the peptide to refold. Treat the Kv4.2 channel with the refolded peptide and measure the IC₅₀ value. If the IC₅₀ value is now 250 nM, does this peptide sequence obey the Anfinsen dogma? Explain.

describe the components of endomembrane system:nuclear envelope,endoplasmic reticulum,golgi appartaus,lysosomes,vacuoles,plasma membrane with their functions and structure

2-3 sentences each,in your own words please

not copy-paste from the internet not even one sentence can be the same as on the internet

Ecologists consider light energy, heat energy, and chemical energy when studying energy flow in an ecosystem. Using these three terms, describe the flow of energy through an ecosystem. Make sure to name the processes that transform energy and at least 2 trophic levels.

PHYLUM ANNELIDA :Compare and contrast Oligochaeta, Polychaeta and Hirudinea. What traits do they share (as annelids) and what traits distinguish each class? ( Similarity vs Difference)

PHYLUM PLATYHELMINTHES (FLATWORMS): compare and contrast the three Platyhelminthes classes( Turbellaria, Trematoda and Cestoda). What traits do they share (as Platyhelminthes) and what traits distinguish each class? ( Similarity vs Difference)

This is BIOchemistry) For the appetite-related signaling molecule MELANOCORTIN:

a.) What is the specific function of that molecule?

b.) What is the mechanism of that action (how does it do what it does)?

c.) How is that molecule made? Describe any prepro- and pro- forms and associated cleavages or covalent bonds or phosphorylations associated with the molecule.

d.) Describe how the molecule is regulated

(This problem relates to chapters 22, Biosynthesis of amino acids, nucleotides, and related molecules; and chapter 23, hormonal regulation and integration of mammalian metabolism, from the Lehninger Biochemistry textbook).

What influences whether your immune system remembers if you have been exposed to an infectious agent or not

Write about 75-100 words

What does BiDil have to do with personalized medicine?

how is DNA changed during transcription? chemically? structurally? be specific

This is BIOchemistry) For the appetite-related signaling molecule GHRELIN:

a.) What is the specific function of that molecule?

b.) What is the mechanism of that action (how does it do what it does)?

c.) How is that molecule made? Describe any prepro- and pro- forms and associated cleavages or covalent bonds or phosphorylations associated with the molecule.

d.) Describe how the molecule is regulated

(This problem relates to chapters 22, Biosynthesis of amino acids, nucleotides, and related molecules; and chapter 23, hormonal regulation and integration of mammalian metabolism, from the Lehninger Biochemistry textbook).

You decide to clone a gene using a plasmid vector featuring ampicillin resistance and the lacZ gene. However, when you try to grow the E. coli onto a plate containing X-gal and ampicillin, you see only blue colonies. Explain what most likely went wrong during the cloning process.

(This is BIOchemistry) For the appetite-related signaling molecule NPY:

a.) What is the specific function of that molecule?

b.) What is the mechanism of that action (how does it do what it does)?

c.) How is that molecule made? Describe any prepro- and pro- forms and associated cleavages or covalent bonds or phosphorylations associated with the molecule.

d.) Describe how the molecule is regulated

(This problem relates to chapters 22, Biosynthesis of amino acids, nucleotides, and related molecules; and chapter 23, hormonal regulation and integration of mammalian metabolism, from the Lehninger Biochemistry textbook).

Why is it difficult for scientists to predict the rate of warming that Arctic regions will experience?

What does “semi-discontinuous” DNA replication mean? Explain in words how the lagging DNA strand is replicated in bacteria. What specific enzymatic activities does DNA polymerase I have? Name each activity and explain its role in DNA replication. If DNA polymerase I lacked its 3’-5’ exonuclease activity, what specific consequences with respect to DNA replication would be observed? What consequences would be observed if, instead of DNA pol I, DNA polymerase III lacked its 3’-5’ exonuclease activity? Explain your answers.