Why would someone choose to do deep sequencing as compared to PCR amplification and sequencing of short sequences?  What are some of the technology platforms used for deep sequencing?

What are the costs of treating bacterial meningitis, responding to, preventing the disease?

Describe in a clear and simple way, in 10 own formulated sentences, how an untreated enamel caries attack can gradually and chronologically lead to the tooth developing a radicular cyst. Each sentence should contain an essential and correct step in the process.

How is much work time lost in suffering from bacterial meningitis?

The following couples plan to marry and want to know the chance of having a child with the following diseases. You are a genetic counselor who needs to answer their questions. Write out the genotypes of the crosses and perform a Punnett square to determine the probability of the child inheriting the disease.

            a. an affected father and carrier mother for color blindness (X-linked recessive)

            b. an unaffected father and a carrier mother for hemophilia (X-linked recessive)

            c. an unaffected father and an unaffected mother for color blindness

            d. an affected father and an unaffected mother for color blindness

Describe how blood flow through the peripheral circulation is regulated during

a) Exercise

b) Hemorrhage How is the mean arterial pressure restored in each case? physiology

Explain how cobalamin can prevent allergies and toxins.

2.a) RNA polymerase adds RNA monomers to where?

Select one:

a. 3' end of the growing RNA transcript

b. 5' end of the growing RNA transcript

c. 5' end of the DNA template

d. 3' end of the DNA template

b) The "charging" of tRNA requires which of the following? Select all that apply.

Select one or more:

a. ATP

b. Aminoacyl tRNA synthetase

c. tRNA lacking an amino acid

d. aminoacyl tRNA

c) Which of the following is/are methods of chromatin remodelling? Select all the apply.

Select one or more:

a. DNA methylation

b. Histone modification

c. tRNA alteration

d. Nucelosome formation

Read the scenario then answer the question:

When Ahmad and Amina decided to get married, they were worried that their coming children might suffer from Sickle cell disease, since Amina’s mother had the disease. But the doctor made things clear ….

DOC: “Unfortunately Mr. Ahmad after tracking your family’s genetics you might be carrying the recessive allele for the disease so there is a 25% chance your children might be anemic. “

PARENTS: “ So does that mean that 25% might not even carry the disease allele?

And 50% will carry the allele but won’t have the disease? Did we mention to you that we are cousins? “

Doctor: “ Well now it makes much more sense! Children of first-cousin marriages have an increased risk of autosomal recessive genetic disorders, just like sickle cell disease, which comes from a recessive allele. Two cousins might both carry the recessive allele and transmit it both to their child which will become ill unfortunately, just like sickle cell disease.

PARENTS: “ Unfortunately, my son Seif was born with sickle cell anemia and is getting medication to carry on his life normally. My daughter Shamsa doesn’t suffer from the disease, but she might carry the recessive gene and might have anemic children in the future. “

-----

INFORMATION:

•You should know that S is the dominant allele for normal blood cells, and s is the recessive allele for sickle cell anemia

•Phenotypes are normal for normal trait and anemic for recessive trait

•In the pedigree we see the cross of the heterozygous parents

question:

Write a neat and full text about your analysis of the family’s inheritance, explain how the disease inheritance is affected by cousins marrying each other, and give solutions to reduce the probability of getting the disease. (350 words)

Enforce your work by doing further research, make sure to insert pictures or any document that you believe can show your work and express your ideas. Do your research on mendelian genetics, inherited diseases, autosomal and gonosomal, patterns of inheritance etc…

The son, Seif, is born with sickle cell anemia. This means both parents carry the allele for sickle cell anemia.

The father, Ahmad has a heterozygous genotype as told by the doctor.

The mother can also be proved heterozygous for the trait since her mother was anemic. This means one of the affected alleles was inherited from the mother.

So, the genotypes of Ahmad is Ss and that of Amina is Ss.

Gametes formed by Ahmad are S and s.

Gametes formed by Amina are S and s.

1 offspring having genotype SS does not carry the affected allele and will be phenotypically normal.

2 offsprings having genotype Ss carry the affected allele but will be phenotypically normal.

1 offspring having genotype ss have both affected alleles and will be sickle cell disease.

X	S	s
S	SS	Ss
s	SS	ss

Question:

Fill the tables by doing the calculations and transforming your results into one ratio, fraction, and percentage for each genotype and phenotype

As such:

ratio 1:2:1, Genotypes: BB ½ , 50%,Bb ¾ 75%                                                  

Phenotype: wrinkled 75%,Smooth 25%

Ratio:
Genotypes
Number
Fraction Form
Percentage

Ratio:
Phenotypes
Number
Fraction Form
Percentage

List and Describe three regulated stages of gene expression (hint there are six to choose from).

I need digital answer thanks?

Give an example of microtubule and a mircofilament in the human body.

IMPORTANT!!! Please answer it precisely. It is expected to use academic knowledge and language. Use your own words, do not copy paste.

Suppose you are a microbiologist living in late 1800ies and early 1900. You suspect that the microorganism called Mycobacterium leprae might be responsible for the disease called leprosy. You had heard about a researcher called Robert Koch and his postulates, and you would like to follow his approach to test if leprosy is caused by Mycobacterium leprae. Explain stepwise and in detail the experimental procedure that you would follow. Please also explain what kind of results you would expect in each step of your procedure.

IMPORTANT!!! Please answer it precisely. It is expected to use academic knowledge and language. Use your own words, do not copy paste.

Please explain in detail how the microbiology information about the infectious diseases and their epidemiology, aseptic techniques of microbiology (sterilization, disinfection, antimicrobial techniques and agents) helped you during the COVID-19 pandemic. Please give detailed examples of how you used your microbiology and/or scientific knowledge in helping/informing people in your family and/or your community and/or how different was your behavior and attitudes than the others (non-microbiology/molecular biology people) around you during the COVID-19 pandemics and the lockdown period.

Pick one of the two options below Option 1: Mini-Mental Status Examination The Mini-Mental Status Examination, originally developed by Folstein, Folstein, and McHugh (1975) in the Journal of Psychiatric Research, vol. 12, pp. 186–198, in the original or revisesd form is commonly used to conduct a quick assessment of dementia and overall mental functioning. Pick four of the main questions and discuss how the answers you might receive from a person might differ if a) the someone appears to ahve h no cognitive impairment versus b) a perosn shows mild cognitive impairment versus c) a perosn shows severe cognitive impairment? Discuss the advantages and limitations of the MMSE? Do not simply quote or paraphrase your references - explain what you learned in your own words. Option 2: Head Injuries Research and read at least two peer-reviewed articles on the topic of head injuries and mental health problems related to sports (football, full contact martial arts, boxing, etc.) or from accidents or combat injuries. Include any issues related to co-morbidity that you found or that you would expect might occur. Describe/summarize what you found in terms of symptoms. How might these symptoms mislead or confuse a mental health practitioner when assessing a patient and about making a diagnosis, for example: a professional assumes a mental disorder (i.e., a depression, bi-polar disorder, personality disorder, etc.) is the main issie, not realizing a person has an unstated history several mild to moderate head concussions, or a history of severe seizures, or a single severe episode of head trauma.