Answer: Untreated enamel caries attack can gradually and
chronologically lead to the tooth developing a radicular cyst in
the following steps
- Dental caries occur when decay causing bacteria make acids in
the mouth which attack the enamel or tooth surface
- Pulpal necrosis or death of dental pulp occurs subsequently,
thus forming necrotic debris which stimulate inflammation. As a
result periapical inflammation occurs
- Then, periapical granuloma is formed which is composed of
granulation tissue, inflammatory cells and scar
- This further provides rich vascular area to the epithelial
rests of mallasez cells (part of peroiodontal ligament cells around
a tooth)
- Due to rich vascular supply, the epithelial rests of mallasez
cells proliferate
- The proliferation of these cells form large mass of cells
- Thus, the inner cells of the mass remain nourishment
deprived
- The nourishment deprived cells undergo liquefaction necrosis
meaning, the mass of cells or tissue is transformed into a liquid
viscous mass
- As a result, a cavity is formed at the centre of the
granuloma
- Persistent and chronic infection results in the formation of
radicular or periapical cyst, which are typically pear shaped or
round and unilocular with a lesion in the periapical region