Kay is the nurse supervisor of a small clinic located on the campus of a Midwestern college. In a single week, she treated fifteen students (ages 19-24) with similar symptoms. They each appeared at the student clinic in various stages of the development of a red macular rash. It seemed to start on the face and spread to the trunk and extremities. Each complained of having had a severe cold, including sore throat, headache, and cough, for a few days previously.

After observing tiny red patches with white centers on the oral mucosa, next to the molars, Kay made her diagnosis. She warned each student that their infection was extremely contagious and placed them in isolation. She also warned them of the need for strict bed rest because of the dangerous complications of this infection. Chemotherapy was limited to acetaminophen for comfort. Kay checked each student’s immunization record and found it complete and up-to-date.

QUESTION 1

Which of these is likely to be Kay’s diagnosis?

A cis-acting mutation that leads to MINIMAL expression of the lac operon would most likely be in the CAP binding site. Is this true or false, and why? Thanks!

You are the Coroner. Identify and explain the MANNER of death in the following scenarios (adapted from Saferstein, 2018, Chapter). Why are you making that determination? In some cases, what more would you need to know about the scene or history?

A. Death due to a motor vehicle accident in which a person lost control of their vehicle in bad weather

B. Death due to a motor vehicle accident in which a person was killed when their car was stopped at a stop sign and they were struck by another vehicle which was street racing.

C. Death due to a contact head wound to the back of the head

D. Death due to carbon monoxide poisoning of an entire family asleep in their beds in different rooms in the house

E. Death due to carbon monoxide poisoning where the body is found in a car parked in a garage

F. Death of a person using fentanyl

G. Death of an elderly person from pneumonia after a fall.

H. Death of an elderly person from pneumonia after being mugged and thrown to the ground

I. Skeletonized remains found in the forest three years after being last seen alive

What role do KNOX proteins have in maintaining the apical meristem?

You are driving to the shops…

1. What information is being detected by you/your body? Provide one external and one internal example. For each, describe how the sensory information is being detected, integrated and processed in the CNS? (2 marks, 2 min)

2. Whilst you are driving a car, what is your body doing to meet its needs/your goals? What is your body doing? Provide one voluntary and one involuntary example. How is the response being generated; what effector pathways are involved? (2 marks, 2 min)

3. Now, tell me about the role of an example protein, expressed on an example cell in one of your examples. What is the protein/where is it expressed/what does it do (and why is this important/relevant)? (2 marks, 2 min)

4. Your protein is dysfunctional. Provide two reasons for why a protein may not be able to fulfil its functional role, and for each, indicate the permanence of this outcome. (2 marks, 2 min)

5. What are the consequences… build from micro to macro: cell/s - tissue/s - organ/s - system/s. Physiologically, what can you not do (and why is that a problem)? (2 marks, 2 min)

Weak interactions among amino acids that stabilize the tertiary structure of the protein include (list five):

A competing commercial effort to sequence the human genome was initiated by the company Celera in 1997. How was their approach different from the Human Genome Project?

• A. Libraries of individual chromosomes were generated and overlapping clones were isolated before sequencing.
• B. They used sequence tagged sites (STS) and expression sequence tags (EST) to order contigs prior to sequencing.
• C. They sequenced the entire genome from one female donor.
• D. They generated overlapping clones from YAC and BAC libraries that were identified by hybridization and organized into long contiguous stretches called contigs.
• E. They used a whole-genome shotgun sequencing method that eliminates the step of assembling a physical map of the genome.

11. Two hypothetical populations of rabbits live on a mountain, one at low elevation and the other at high elevation. Rabbits at the low elevation experience a mild climate and have short fur, whereas rabbits at the high elevation are exposed to cold conditions and have long fur. There are no geographic barriers separating the ranges of two populations.

An ecologist finds that in both the low and high elevation populations, there are a few rabbits that have intermediate fur length. She notes that the rabbits with intermediate fur length can successfully mate and produce offspring with rabbits that have short or long fur.

What is the most likely explanation for why some rabbits have intermediate fur length?

A) The rabbits with intermediate fur length are a seperate species.

B) The population at low elevation is experiencing genetic drift.

C) The rabbits with intermediate fur length live in a different area and are migrating through the two populations.

D) There is a gene flow between the low and high elevation populations.

1.) During Phloem transport, which of the following occur at, or close to the SINK? Select all that apply

a. Sugars move out of sieve tubes by active transport.

b. Sugars move into sieve tubes by active transport.

c. Water moves from the xylem into the sieve tubes

d. Water moves from phloem into the xylem.

e. Solution in sieve tubes becomes hypertonic

f. Solution in sieve tubes becomes hypotonic.

g. Tugor pressure decreases

h. Tugor pressure increases

A species of mouse F1 testcross gave rise to the F2 phenotypes:

Short hair wildtype, short tail 625 Short hair wildtype, long tail wildtype 48 Long hair, long tail wildtype 645 Long hair, short tail 39

Q1. a) Do the genes appear to be linked? Answer yes, no, or maybe. 1 mark b) Explain your answer. 2 marks

Q2. a) What do the phenotype numbers tell you about recombination frequencies of these alleles during meiosis? 1 mark

b) How does this relate to linkage? 2 marks

Q3. What is the genotype of the testcross individual? 2 marks

Q4. What is the genotype of the F1 female? 2 marks

To avoid the loss of terminal sequences different organisms use different strategies to replicate their DNA.

A. What features of the chromosome does E. coli have to circumvent this problem? Provide a detailed answer.

B. What strategy do prokaryotes use to replicate linear chromosomes to circumvent this problem? Provide a detailed answer.

C. What strategy do eukaryote use to replicate chromosomes to circumvent this problem? Provide a detailed answer.

What are the functions of fats and lipids list 5 things

Distinguish between "good" and "bad" cholesterol. In your discussion, include descriptions of HDL and LDL explaining which type of cholesterol is detrimental to your health and why.

Format: 12 point font, Times New Roman, double-spaced, APA format.

1. Which checkpoint and phase of the cell cycle is the expression of BRCA1 and BRCA2 the greatest? What is the function of BRCA1 and why would it make sense that its expression is high at the checkpoint/phase of the cell cycle?

2. Outline the two parts of the eukaryotic cell cycle and describe the three main checkpoints in cell cycle regulation.