inThe citric acid cycle there are three reactions of the citric acid cycle it's self that...

inThe citric acid cycle there are three reactions of the citric acid cycle it's self that are regulated:

-citrate synthase which is where ATP inhibits in in citeo

-isocitrate dehydrogenase: alosterrically activated by Ca2+ and ADP also is inhibited by NADH

- alpha ketoglutarate dehydrogenase which is where Ca2+ increases the rate of formation of succinyl-CoA

what would happen if all three of these reactions were not present? what would happen if citrate synthase was not functioning, what would happen if only isocitrate dehydrogenase was not working, what would happen of alpha ketoglutarate was not working?

Expert Solution

Citrate synthase, isocitrate synthase, and alpha-ketoglutarate dehydrogenase are the important enzymes in citric acid cycle. The activation or inhibition of these enzymes: synthases and dehydrogenase results in the formation of varying amount of their products.

When citrate synthase, isocitrate synthase, and alpha-ketoglutarate dehydrogenase were not functioned properly, it would effect citric acid cycle negatively.

gladiator answered 1 year ago

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