1. Phenylketonuria (PKU) is an inherited disorder in which a mutation in a single autosomal gene leads to inability to break down the amino acid called phenylalanine. Babies born with PKU often have the following symptoms: a musty odor to the skin, hair, and urine; vomiting and diarrhea; irritability; itchy skin, and sensitivity to light. If this condition goes untreated, it can lead to the loss of skills, growth and developmental delays and seizures. The term that best fits with this description of PKU is:

2.

PKU is inherited as an autosomal recessive disorder. Bob and Jan are healthy. Bob is not a carrier of this disorder, but Jan is a carrier of the PKU allele (She is heterozygous.). If they have a child, what is the probability that this child will show the disorder PKU (have the phenotype for PKU)?

3.

PKU is inherited as an autosomal recessive disorder. Bob and Jan are healthy. Bob is not a carrier of this disorder, but Jan is a carrier of the PKU allele (She is heterozygous.). If they have a child, what is the probability that this child will show the disorder PKU (have the phenotype for PKU)?

4. Huntington disease is inherited as an autosomal dominant disorder with adult onset. Sally has Huntingon disease (She is a heterozygote for this gene). Her partner John does not have Huntington. Suppose Sally and John have 3 children. What is the probability that NONE of their children inherit Huntington Disease?

CODIV-19 has been sweeping across the globe, rendering all physical interaction hazardous, as such, most people and businesses opted to use remote and distant approaches. With that in mind, Provide a comparison of three physical solutions that have been substituted with virtual solutions.for eg: students going to  university now have classes online,so the physical solution has been substituted to virtual solution

(Please justify your answer) A rare mutation generates a fourth blood group, C, where they are missing one additional carbohydrate from the glycoprotein, i.e. type I with one more sugar missing. What ABO blood groups could donate to this individual?

Flower color in a diploid plant is governed by a single gene with 2 alleles (C^R and C^W). Inheritance of flower color follows a pattern of simple Mendelian genetics with dominance.

Scoring of 1850 plants gives the following data:

Flower Color                 Genotype    Number

Red    C^RC^R   467

Red                                     C^RC^W      946

White                                  C^WC^W      437

a) The allelic frequency of C^R is [A] (enter your answer as a decimal rounded to three significant figures after the decimal, in the form '0.xyz'; be sure to round off correctly).

b) The allelic frequency of C^W is [B] (enter your answer as a decimal rounded to three significant figures after the decimal, in the form '0.xyz'; be sure to round off correctly).

Now, assume that this population is in Hardy-Weinberg (H-W) equilibrium at the flower color locus.

c) Under the assumption of H-W equilibrium, the expected frequency of dominant homozygotes with red flowers under is [C] (enter your answer as a decimal rounded to three significant figures after the decimal, in the form '0.xyz'; be sure to round off correctly).

d) Under the assumption of H-W equilibrium, the expected frequency of heterozygotes with red flowers is [D] (enter your answer as a decimal rounded to three significant figures after the decimal, in the form '0.xyz'; be sure to round off correctly).

e) Under the assumption of H-W equilibrium, the expected frequency of recessive homozygotes with white flowers is [E] (enter your answer as a decimal rounded to three significant figures after the decimal, in the form '0.xyz'; be sure to round off correctly).

A chi-square goodness-of-fit test is performed, The chi-square statistic = .898 and the P value is between 0.5 and 0.1.

f) This population of plants [F] in Hardy-Weinberg equilibrium (enter either 'is' or 'is not' in the space provided).

2.WHAT CHARACTERISTICS OF BEETS MAKE THEM USEFUL AS EXPERIMENTAL MODELS FOR STUDYING CELLULAR MEMBRANES?

3. EXPLAIN WHY PHOSPHOLIPIDS HAVE A NATURAL TENDENCY TO SELF ASSEMBLE INTO A BILAYER.WHY IS THIS BIOLOGICALLY IMPORTANT?

4. As it turns out, studying banthas is too dangerous for you, and you decide to turn your attention to a much less hostile organism, the Ewoks. You begin another project. You find that you have to count hundreds of ewoks. You are committed to the new project, but you secretly wonder if you shouldn’t have stuck with banthas.

You are studying two genes known to be linked, fur color and height.

• If two genes are linked, where are they located in relation to one another in the genome?

• Do two genes showing linked inheritance have to show a related function? Why or why not?

• After you perform your cross, you get the following result:

725 Brown fur, short ewoks

255      Tan fur, tall ewoks

12        Brown fur, tall ewoks

8          Tan fur, short ewoks

What is the recombination frequency between wing shape and body color? Show your work.

1. Explain how covalent catalysis contributes to the function of the serine protease.
2. Examine each of the different major classes of proteases. In what way is the mechanism of each class similar, and different, to the serine protease mechanism?

How is evolution affecting us/our world right now, as we speak?

10. In Saccharomyces cerevisiae, cell type is determined by which genes are present at the MAT locus. Describe the function of the a1, 1 and 2 proteins in each of the three cell types (a-haploids, -haploids and diploids).

Anion exchange chromatography

1. In the purification, the pH of the PBS buffer was 6.5, and the two proteins have different isoelectric points (Haemoglobin pI: pI 6.8; Catalase: pI 5.4). What are the charge states of the two proteins at this pH? (e.g. positively charged, negatively charged or neutral)

2. Based on the charge states of the proteins, which protein has a higher affinity to the DEAE-Sepharose resin at pH 6.5?

3. Why was the salt concentration of PBS buffer increased (from 17.5 mM to 175 mM) in order to elute out the catalase protein?

Chlamydia trachomatdryisis an obligatekml intracellular parasite and cannot be cultured in artificial media. The commonly used method for detecting this organism is _________________
a)polymerase chain reaction
b)selective liquid media
c)growth selective media
d)chlamydia trachomatis selective

In the fruit fly Drosophila melanogaster, wild type eye color is a brick red color and is produced by the action of two genes, one producing red color, the other brown. Vermilion is an X-linked recessive mutation that results in a bright red eye. Brown is an autosomal recessive mutation that results in a brown eye. Flies carrying both the vermilion and brown mutations produce no pigment and have white eyes. True breeding Vermilion eyed females are crossed to brown eyed males

a. Determine the genotype of the parental flies

b. Diagram the cross and determine the F1 genotypic and phenotypic ratios

c. Diagram the cross when the F1 progeny are mated to produce an F2 generation. Determine the F2 genotypic and phenotypic ratios. You must correctly use the forked line method (branch diagram).

How do amphiphilic emulsifiers work in the emulsion?

List and briefly describe 4 functional properties of sugars (i.e. how these affect food systems)?