Question

Match the region of the antibody with its correct function by using the following two options a) Fc b) Fab

1. if an antibody was attached to a virus, this region would be specifically binding to the virus 2. this region is always different between IgG and IgE 3. this region contains the variable regions of the heavy and light chains 4. this region contains the constant region of the heavy chain 5. this region determines the isotype of the antibody 6. if an opsonizing antibody was attached to a virus, this region could bind to receptors on a phagocytic cells and then signal for the virus/antibody complex to be phagocytosed

Answer 1

the Fc contains only constant domain of the heavy chain, but Fab contains both variable and constant regions of both heavy and light chains.

the variable region binds to the virus, and the constant region ( the Fc ) binds to the receptors of the phagocytic cell so that the virus or other antigens to which the antibody is bound can be phagocytosed.

the variable region is different in different antibodies.

Isotypes have different constant regions of the heavy chain.

1 ) if an antibody was attached to a virus, this region would be specifically binding to the virus - Fab-b

2) this region is always different between IgG and IgE-a) Fc.

3) this region contains the variable regions of the heavy and light chains- b) Fab

4) this region contains the constant region of the heavy chain- a) Fc

5) this region determines the isotype of the antibody - a) Fc

6) if an opsonizing antibody was attached to a virus, this region could bind to receptors on phagocytic cells and then signal for the virus/antibody complex to be phagocytosed- a) Fc