I have an issue understanding maternally and paternally imprinted gene questions.

Here are some examples:

1. A phenotypically normal man named John is heterozygous for a deletion on chromosome 15 that contains the maternally imprinted gene SNPRN gene. Absence of SNPRN gene function results in Prader-Willi syndrome. The man marries a normal woman named Jane who does not carry the deletion. They have 2 children. Which of the following statements is FALSE?

A. John inherited the chromosome with the deletion from his mother

B. There is a 25% chance that both children will have Prader-Willi syndrome

C. Half of John's sperm contain a version of the SNPRN gene that would be expressed in his children

D. All of Jane's eggs contain a version of the SNRPN gene that would be expressed in her children

E. in Jane's somatic cells, there is one active copy of the SNRPN gene.

The answer is D, but how are choices B and E true? I'm in a genetics course at a university so being detailed would be helpful please.

2. The Igf2 gene in mice encodes a growth factor gene whose expression is necessary for normal size. The absence of the Igf2 gene products results in small mice. The Igf2 gene is a maternally imprinted gene, meaning it gets inactivated during oogenesis in females. A normal-sized female mouse heterozygous for a deletion of the Igf2 gene gives birth to a normal-sized male. This male is then crossed to a normal female (no deletion). Assuming that this male inherits the Igf2 deletion from his mother, what fraction of the progeny from this male will be small?

A. 1/4 B.0 C.1/2 D.1/3 E.1

The answer is C, but again I don't understand why.

Q. We have a recombinant inbred line population in the F10 generation (NOTE THAT THIS IS A RECOMBINANT INBRED POPULATION (RIL), NOT AN F2 POPULATION). In this population, it was observed that there were 62 RILs with purple flowers and 38 RILs with white flowers.

1. What is the expected number of individuals for each class if a single dominant gene conditions purple flower color? For example, the parents used to produce the RIL population could be WW x ww.

2. Calculate the Chi-square statistic for this expected ratio.

3. Does the observed number of purple vs white fit the expected ratio for a single dominant gene at the 0.05 level of probability?

Why would we choose a cDNA library over a genomic DNA library? In other words, what is the difference between the two?

Find and analyze an article (first published in the last 28 days) about some topic dealing with nutrition and/or exercise addressing a hypothesis. This can come from a newspaper, magazine or other periodical.Analyze the article and address the following:

1. What hypothesis was tested?

2. How was it tested?

3. Was the hypothesis supported or rejected?

4. Is the sponsor of the science mentioned? This could be a university where research was conducted, a company that supplied funding, etc. Do you think the sponsor may have influenced the science? By that I mean do you think the source of funding could lead to a conflict of interest?

5. What are some implications of this research?

6. What could you do if you wanted to find out more about the topic? Be more specific.

Make a comparative chart on the main methods of protein quantification.

Which of the following would normally alter the affinity of an enzyme for its substrate? Select all that apply.

answer choices

a.pH

b.Temperature

c.Ionic concentrations

d.Enzyme concentration

Outline the process of producing vaccines. Write a mini essay on vaccination, detailing the principle of vaccination preparation, development of new vaccines, the routes of administration and side effects. Briefly touch on vaccine controversy.

as an exercise physiologist what activities and educational modules they recommend for kids in terms of physical activity and physical fitness, eating for healthy living and community cohesiveness ?

Describe one example of cellular (either cells within a multicellular organism or unicellular organisms) where population genetics involved in survival of the cell type through at least one mechanism.

What are some of the ecosystem functions that were lost in the Pleistocene that rewilding might help regain?

1. List the 7 characteristics of living things and provide a definition of each. Fig 1.1
2. Distinguish among the three domains of life.
3. After being given a description of a living organism be able to appropriately classify which domain it belongs to.
4. List and distinguish among the three kingdoms of multicellular, eukaryotic life. (Plants, Animals, Fungi)

You isolate a new pathogenic bacteria, from the sputum of a human patient, which you hypothesize was the cause of a severe respiratory infection. How could you use Koch’s postulates to prove your hypothesis? Which postulate would not be satisfied if the organism was a human-only pathogen?

1. Based on the human variation, why do most people misunderstand the concept of "race"? Instead of using the concept of race to describe human variation, what would be a better explanation for human diversity?

2. What can we learn about the falsehoods of race as a biological concept? How this should be taught in schools?

Imagine a space alien, Flapper, lands on the planet, and asks about the history of life on earth. You are tasked with providing Flapper evidence of evolution, using examples from biology, and are given unlimited resources to show and tell whatever you would like that helps you explain.What are 2 different types of evidence supporting the evolutionary concept of descent with modification that you would use? Please describe how you would explain them to Flapper, using specific examples.