Question 3 You are doing genetic studies on a family that has several members with a particular disease. You identify a gene with a one base pair difference (C→T) between the patients (T) and a healthy relative (C). This gene encodes a protein that acts as an enzyme in cellular metabolism.
(A) Describe two ways in which a C→T mutation in the DNA could cause a loss-of-function disruption in a protein.
(B) Describe how it is possible that a loss-of-function mutation can be dominant to wild-type
(C) Describe three potential consequences of a loss-of-function mutation in the protein described in (A). (Answer could be at a cellular or organismal level.)
(D) Describe two ways in which a C→T mutation in the DNA could cause a gain-of-functiondisruption in a protein.
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Which of these DNA sequences is palindromic when double-stranded?
A) 5-ATGGTA-3
B) 5-GGGCCC-3
C) 5-ATCCAT-3
D) 5-ATGATG-3
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hello I would like to know the concept of micro and macro domains and the correlation to loop formation in bacterial chromsomes, specfics such as base pairs ectera as well. And also why not all bacterial species contain micro and macro domain
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What traits are most likely influenced by genes and what traits are most likely influenced by the environment? Explain your reasoning.
200 Words at least
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A homozygous polled Hereford bull (with dominant hornless gene (PP) , dominant white-face spotting pattern (WW) and recessive brown coat color (bb) is crossed to an Angus female with horns (recessive, pp), no spots (recessive, ww) and a dominant solid black coat color (dominant, BB). All the F1 animals are polled (hornless), have a solid black coat and a white-face spotting pattern. These three loci are autosomal and independent from each other. The F1 animals are crossed to F1 animals to produce an F2. How often are horned, white-face and black animals expected in the F2?
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Animal science problem, be sure to know the answer before u answer it thanks
How are feed intake, ruminal rate of passage, ruminal pH regulation and body weight gain related to each other?
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You are a prominent cancer scientist leading a government laboratory, you just received bottle of colon cancer biopsy along with some normal colon tissue collected from a patient.
(A) Describe and give examples of the traditional ways and modern omics methods you would use in classifying this colon tumor tissue.
(B) After a week, additional clinical testing results of the
patient came back, the colonoscopy failed to find any polyps, and
your latest lab test result also indicated the MLH1 gene expression
was lost in the tumor sample.
1. Based on these data, which genetic disease would you
suggest the patient is suffering from? (1 mark)
2. Name and describe the cellular process by which of
MLH1 is involved; and outcome of losing MLH1 gene expression .
3. Name and describe the molecular basis of the process
by which often involved in driving diminished expression of MLH1 . Describe also molecular mechanism a normal cell would use
to counter act the “process” .
(C) Describe in details the advanced laboratory techniques by which you could use to study the “process” occurred to the MLH1 locus.
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Using your data and the fact that plants are roughly 44.5% carbon, calculate how many days it would take for all of the carbon in your leaves to be respired if microbes continue to metabolize at the rate you measured. Now, think back to a just-fallen leaf outside. Considering how many days you estimate it would take your leaves to disappear, do you think there are enough days that are moist and warm enough to allow complete metabolism of leaves between fall and spring, say between November 1 and May 15? Explain.
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Assuming 2 ATP per NADH and 1 ATP per FADH, how many moles of ATP can be generated in E. coli cell when one mole of arachidonic acid (20:4) is completely oxidized during beta-oxidation? Assume only FADH is produced during beta-oxidation.
a. 93 ATP/mole 20:4
b. 94 ATP/mole 20:4
c. 95 ATP/mole 20:4
d. 96 ATP/mole 20:4
e. 97 ATP/mole 20:4
f. 98 ATP/mole 20:4
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. Gradualism is an important assumption of evolutionary theory.
A. A complex structure like the eye would be unlikely to emerge from a single large-scale mutation. How does gradualism help evolutionists address the evolution of complex adaptations, such as the eye?
B. How do ring species support a gradualist model of speciation? Explain.
2. Use the comparative method to answer the following questions about selection and adaptation, discussed Chapter 8.
A. What are convergent evolution and divergent evolution?
B. Why would selection ever delete a trait after having built it? Explain how cave-dwelling species lost the eyes that had evolved in their ancestors.
C. Why are disabling mutations in an olfactory receptor gene more likely to be “tolerated” by selection in a species with full trichromatic vision than in species without it?
D. Do you see parallels between increased loss of olfactory genes in species with trichromatic vision and the evolution of eyelessness in cave-dwelling species? Explain.
3. Altruistic traits, by definition, harm the individual manifesting the trait and help others.
A. What does Hamilton’s Rule say about the conditions under which kin selection should favor altruism?
B. In the woodpecker nest-helper example from class, explain how it can be in the evolutionary interests of a young bird to help their mother or sister breed when there are not enough nest holes to breed on their own.
C. Even when there are nest holes available, young birds sometimes help their mothers breed instead. How do “Selfish Genes” explain the evolution of behavior that is not in the interests of the individual (not facultative altruism).
D. In the case of reciprocal altruism, explain how reciprocity can maintain altruism even without close genetic relatedness.
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What is/are the energy source(s) utilized by primary producers in the hydrothermal vents on the ocean floor?
(a) light
(b) sulfur compounds
(c) organic molecules
(d) carbon dioxide
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Which type of protein is very important in all of the following: skin, bone, cartilage, and basal lamina? A. Elastin B. Collagen C. Proteoglycan D. Laminin E. None of the above
Which mutation would be more severe? A. Glycine to alanine B. Glycine to arginine
Interactions between cells and the ECM regulate: A. Cell polarity B. Cell growth C. Cell differentiation D. Cell motility E. All of the above!
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Please assist me with this question regarding the case of "Community Blood Center of the Carolinas: Donations, Donations, Donations."
Complete and Answer the following questions:
Make sure that you include an introduction and conclusion to your post.
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