different between MHC class 1 and MHC class 2 (Table)

Expert Solution

	MHC class I	MHC class II
Types of antigen presenting cells	These are present in all nucleus cells	These are present on specialised APCs like macrophages, bacteria and dendritic cells.
Peptide size and structure	Contains 8 to 10 amino acids and consist of one membrane spanning alpha chain.	Contains 14 to 20 amino acid and consist of two membrane chains alpha and beta of similar size..
T cells response	These are present on the cytotoxic T cells lymphocytes including CD 8 and T cells.	These are present to helper T cells lymphocytes of CD4 and T cells
Coreceptors responsible	Bind with CD8 coreceptors cytotoxic T cells.	Binds with CD4 of helper T cells
Enzyme responsible to peptide generation	Cytosolic proteasomes	Endosomal and lysosomal proteases.
Site of peptides loading	Endoplasmic reticulum	vesicular compartment
Presentation of foreign antigens	Intracellular	Extracellular
Final outcomes	Target cell for destruction	Induces antibody production.

gladiator answered 2 years ago

Briefly describe presentation by MHC class I molecules and give 2 comparisons where MHC class II...

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