different between MHC class 1 and MHC class 2 (Table)

Solutions

Expert Solution

	MHC class I	MHC class II
Types of antigen presenting cells	These are present in all nucleus cells	These are present on specialised APCs like macrophages, bacteria and dendritic cells.
Peptide size and structure	Contains 8 to 10 amino acids and consist of one membrane spanning alpha chain.	Contains 14 to 20 amino acid and consist of two membrane chains alpha and beta of similar size..
T cells response	These are present on the cytotoxic T cells lymphocytes including CD 8 and T cells.	These are present to helper T cells lymphocytes of CD4 and T cells
Coreceptors responsible	Bind with CD8 coreceptors cytotoxic T cells.	Binds with CD4 of helper T cells
Enzyme responsible to peptide generation	Cytosolic proteasomes	Endosomal and lysosomal proteases.
Site of peptides loading	Endoplasmic reticulum	vesicular compartment
Presentation of foreign antigens	Intracellular	Extracellular
Final outcomes	Target cell for destruction	Induces antibody production.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Briefly describe presentation by MHC class I molecules and give 2 comparisons where MHC class II...

Briefly describe presentation by MHC class I molecules and give 2 comparisons where MHC class II presentation is different.

Compare and contrast MHC class 1 vs MCH class 2: what are they? What do they...

Compare and contrast MHC class 1 vs MCH class 2: what are they? What do they present? Which cell lines express (have) them? Which immunity cell lines perceive (bind with) them? Which receptors are then used by those immunity cells to perceive them?

describe the process of antigen presentation by MHC-1 and MHC-2

3. Describe the structure of a class I MHC molecule AND a class II MHC molecule...

3. Describe the structure of a class I MHC molecule AND a class II MHC molecule with the following prompts: a. number of polypeptide chains b. domains of each polypeptide chain, including transmembrane and cytosolic domains c. secondary structure d. domain composition of the peptide-binding site e. details of the architecture of the peptide-binding site f. size of the peptide that can bind

51. What is true about MHC class 2 molecules? A) The CD8 surface protein is needed...

51. What is true about MHC class 2 molecules? A) The CD8 surface protein is needed for attachment B) Present exogenous antigens C) Are found on red blood cells. D) Trigger release of perforins and fragmentins E) All of the above 52. Which is false about neuronal development? A) The brain grows by 2/3 in the first three months after birth B) Neurons begin to develop by week 3 of embryonic development. C) In adolescence, new neurons are added to...

1. What kind of cell is most likely to interact with a class I MHC protein...

1. What kind of cell is most likely to interact with a class I MHC protein on a cell surface? 2. The antibody-combining site binds to a part of the antigen that is complementary to the combining site. What is this portion of the antigen called? 3. Which T cell is most likely to be stimulated by the appearance of exogenous antigens presented by an antigen-presenting cell? 4. What properties of fibronectin and other similar molecules of the ECM allow...

1) Class II MHC molecules are found on which of the following? liver cells and macrophages...

1) Class II MHC molecules are found on which of the following? liver cells and macrophages in the spleen granulocytes and microphages red blood cells lymphocytes and antigen-presenting cells all body cells with a nucleus 2) Histamine increases blood flow and vascular permeability. This would account for all of the following changes that occur during inflammation except heat of the inflamed tissue. swelling of the inflamed tissue. movement of defense proteins and cells into the interstitial space. chemotaxis of phagocytes....

1. Transplant between individuals of the same species that have differences in the MHC antigens: a....

1. Transplant between individuals of the same species that have differences in the MHC antigens: a. allograft b. Isograft c. Autograft d. Xenograft 2. In the following scenario is there any chance for graft versus host disease to occur. A patient is diagnosed with a severe acute leukemia requiring treatment that will destroy tumor cells, but also their bone marrow. This treatment will require a bone marrow transplant to restore immune function. The transplanted bone marrow will come from an...

Which type of MHC class molecules is found on all nucleated cells and is used to...

Which type of MHC class molecules is found on all nucleated cells and is used to communicate with cytotoxic T-lymphocytes? Which class is found only on APCs and is used to communicate with helper T-lymphocytes? Where does a lymphocyte typically encounter an antigen for the first time? Describe how both helper T-lymphocytes and cytotoxic T-lymphocytes are activated. Is a separate APC required for B-lymphocyte activation, or is a B-lymphocyte able to serve the role of an APC? What are the...

DROP DATABASE class;CREATE DATABASE class;Use class;drop table if exists Class;drop table if exists Student;CREATE TABLE Class...

DROP DATABASE class;CREATE DATABASE class;Use class;drop table if exists Class;drop table if exists Student;CREATE TABLE Class (CIN int PRIMARY KEY, FirstName varchar(255), LastName varchar(255), Gender varchar(1), EyeColor varchar(50), HairColor varchar(50), HeightInches int,CurrentGrade varchar(1));CREATE TABLE Student (SSN int PRIMARY KEY,FirstName varchar(255),LastName varchar(255), Age int,BirthMonth varchar(255),HeightInches int,Address varchar(255),City varchar(255),PhoneNumber varchar(12),Email varchar(255),FavColor varchar(255),FavNumber int);INSERT INTO Class VALUES(1, "David", "San", "M", "BRN", "BLK", 72, "-");INSERT INTO Class VALUES(2, "Jeff", "Gonzales", "M", "BRN", "BLK", 68, "B");INSERT INTO Class VALUES(3, "Anna", "Grayson", "F", "BRN", "BRN", 62,...

Subjects