1. Transplant between individuals of the same species that have differences in the MHC antigens: a....

1. Transplant between individuals of the same species that have differences in the MHC antigens: a. allograft b. Isograft c. Autograft d. Xenograft

2. In the following scenario is there any chance for graft versus host disease to occur. A patient is diagnosed with a severe acute leukemia requiring treatment that will destroy tumor cells, but also their bone marrow. This treatment will require a bone marrow transplant to restore immune function. The transplanted bone marrow will come from an identical twin.

a. Graft versus host disease is very possible b. Graft versus host disease in very unlikely

3. This almost instant type of rejection is a result of the action of preformed antibody and C’ against MHC antigens: a. Acute rejection b. Chronic rejection c. Hyperacute rejection d. Acute cellular rejection

4. In order to perform serologically based tissue typing prior to performing a transplant you need which of the following to perform the test: a. C’ b. Donor and recipient lymphocytes c. Antibodies to the MHC surface markers d. All of the above

5. The best anti-rejection drugs that are able to be tolerated for long periods of time are: a. Cytokine interfering agents that suppress a specific action such as blocking IL-2 or IL-2r such as cyclosporine b. Anti-inflammatory drugs such as corticosteroids c. Cytotoxic drugs that interfere with DNA replication d. Anti-lymphocyte antibodies

Expert Solution

gladiator answered 2 years ago

different between MHC class 1 and MHC class 2 (Table)

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