Question

describe Eldepryl drug. its trade name, classification, action, uses, dosage and route, side/ adverse effect, contraindication, precaution, pharmacokinetics, onset, peak, duration, interactions( decrease, increase), nursing consideration ( assess, administer, perform/ provide, evaluate, teach patient/ family)

Answer 1

trade name, :-Selegiline

classification:- ,CNS stimulants( enzyme inhibitor)

action,:-MAO inhibitor

uses, :-Parkinson's disease

           1) in addition to levodopa

           2)it decrease the dose of levodopa

         3) it delays the development of dyskinesia, tremor

dosage and route,

10mg/day in divided dose

age	dose	route
60 -65	5mg per day	oral
66-70	6mgper day
71- 75	8 mg/day
75-80	9 mg/day
80 and above	10 mg/day

side/ adverse effect,:- dizziness

abdominal pain

dry mouth

nausea

contraindication,:- convulsive disorder

heart disease

psychiatry illness( mood disorder , schizophrenia)

headaches

liver disease

overactive thyroid

hypertension

hypersensitivity

pregnancy

breastfeeding

precaution,   :-

- don't drive after intake of the drug

-caution in patient with peptic ulcer disease

-get up from bed or lying down slowly (cause dizziness)

pharmacokinetics, onset, peak, duration,

peak at 30 minutes to one and half hour

duartion:- 10 hours

interactions( decrease, increase), :-

increase amount of selegiline in blood	decrease elimination of selegiline
SSRI	AMODIAQUINE
TRAMADOL
METHADONE
OPIOIDS

SEROTONIN TOXICITY:- if taking along with drug which increase serotonin on blood.

nursing consideration

- assess for any other drug intake

- administer the total dose in divided dose

watch for toxicity

-do not drink alcohol

-donot stop drug abruptly.