Question

describe Teciferda drug. its generic name, classification, action, uses, dosage and routes, side effects, contraindications, precautions, pharmacokinetics, onset, peak, duration, interactions ( decrease, increase), nursing consideration ( assess, administer, perform/ provide, evaluation, patient teaching).

Answer 1

Teciferda (Tecfidera)

• Generic name:Dimethyl fumarate
• Classification :Immunomodulator
• Action :After the administration of the drug ,this will gradually decrease the inflammatory response and the damage occurring in the nerves. As a result the symptoms are controlled and prevented
• Contraindication :Pregnancy, nursing mother ,hypersensitivity ,allergies
• Precautions :
  • Inform the provider in case of any infection
  • Pregnancy planned to be informed
  • In case of use of any herbal supplements
  • Lymphopenia
  • Herpes infection
• Pharmacokinetics :The drug us hydrolysed and concerned to monomethyl fumarate .The T max is about 2-2.5hours and nearly 27-45% are bonded to protein. Nearly 60% if the drug is eliminated from the body through the carbon dioxide and rest by stool and renal system
• Onset: in about 1hour to 24 hours
• Peak:2-2.5hours
• Duration : about 2years
• Interactions :
  • Certain antibiotics
  • Diuretics
  • During chemotherapy treatments
  • It intetacts with vaccines which are live
• Nursing Consideration :
  • Assess for any adverse reactions
  • Assess for changes in liver enzymes and renal profile as per order
  • Inform the patient for report any type of abnormalities or changes or any sideegfy
  • No OTC medication
  • Follow aseptic procedure to prevent infection
  • Assess for skin changes
  • Infection control practice to prevent infection
  • To take medication only as directed ,not to overdose or underdose
  • Missed dose can be taken when remembered .In case if the time is near to next dose just skip the missed dose and take the next dose