1. Select statements that are true regarding the function of the protein with the sequence provided below: MKSKILYGPSPVYPLESGTGGEHIHKYISKYAKIPGCVAMTNAHTKENLFYAELVELTCKLAHSLKRYGVTQESTIAVCSENSLQYFIPMISGLYIGAVTAAVSDKYDERELISCLNLSKPSLVFCSQQTLAKILQVKPKLDYIKKILVLDSVDNVDSMQSMHNLILKHCHPDFDVKHFKPDSFNDQKVAMILNSPGSTGLPKGVMLTHKNLLVRFCHCKDPIFGNQISPGTAILTAIPFPHGFGMSTVLGYLTCGFRIVLMHTFDSQLYLQSLQDYNVESTVMVPTLMTFFAKSPLVENYHLPNLKEIASGGAPLSKEIGEAVAKRFKLRTIRQGYGLTETTSTILITAAGEVVPGSTGRLVPFFAAKVVDCTSGEALGSNEVGELYFKGDMNMKGYCNNPEATAEMIDNDGWLHSGDLGYYNETGHFFIVDRLKSGIKYKGYQVAPAELEGILLTHPSIMDAGVTGIPDEYAGELPAACVVLKPGHNITEKSLVNYVSSRVSSVKKLRGGVRFVDEIPKGSTGKIDTRALKEILQKPKSHL *

• It is an enzyme.
• The sequence is an exact match to Aquatica lateralis.
• The substrate for the enzyme is luciferin.
• The substrate for the enzyme is luciferase.
• The protein is found in firefly species.
• The protein sequence is not an exact match to any known firefly species.
• The sequence is from the Kampung Kuantan fireflies.
• The protein is involved in bioluminescence.
• The protein is a fluorescent protein.

2. For the protein sequence provided below; identify the function of the protein. Select other statements that are TRUE regarding that protein sequence. //Protein sequence: MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT *

• The protein is to be able to interact with an enzyme called Angiotensin Converting Enzyme 2.
• The protein is a recognizable feature that gives the name to a specific group of related viruses when the virus is studied using electron microscopy.
• The protein is called a corona protein and is composed of lipid chains that is the reason why coronaviruses can be degraded by soap.
• There are no available structures of this protein.
• Homologs of this protein can also be found in bats.

1)

Water has a high boiling point and low freezing point, high self-cohesion, and lower density in the solid phase than in the liquid phase. All these properties can be attributed to ______________.

2)

Based on your knowledge of relative electronegativities among the elements common in living cells, which of these chemical groups containing hydrogen would be most likely to participate in forming a hydrogen bond? "R" represents the rest of the molecule.

3)

In the lining of your stomach, ATP is hydrolyzed to ADP and phosphate ion by a transporter, releasing energy that is used to pump protons (H⁺) from interstitial fluid into the stomach lumen. We learned that energy can make a mass accelerate over a distance. What is the mass and what is the distance in the H⁺ transport system?

Explain what steps should be taken to combat an epidemic (20marks)

Given the sequence below

5’ AACTTCGGCTTAAATGGAGGCCAT’

1. What is the complementary DNA strand?
2. What would the mRNA strand look like?
3. What would the protein look like?
4. Create a point mutation in the DNA and then give the mRNA and protein sequence.
5. Create a frameshift mutation in the DNA and then give the mRNA and protein sequence.

Describe why pH has an effect on the tenderness of meat.

Summarise the three main postmortem stages involved in the conversion of muscle to meat.

What is a reporter gene construct? b. Where did the reporter gene come from? What is its normal biological function? c. How was the expression of the reporter gene controlled? d. What information did the use of the reporter construct give the investigators?

List and describe the early stages of animal development, beginning with fertilization. Then describe two similarities and two differences between early plant and animal development.

Describe intracellular trafficking of CI-M6PR, with names of specific molecules involved in the process, and its role in mechanism underlying I-cell disease.

Compare the osmoregulatory challenges faced by saltwater and freshwater fish, and the ways in which their bodies achieve homeostasis with regard to osmoregulation.

Compare and contrast the roles of GNRH, LH, FSH and steroid hormones in the regulation of gametogenesis in human males and females.

Discuss the significance of antigenic drift and antigenic shift

Has WHO learned it’s lesson from Ebola in handling COVID-19? Why or why not?

Chlor?uazuron, Oxymatrine, and Spinosad (insecticides) were different in their activity for inhibition of AChE and ATPase in honey bees, what is the reason? Why is the rate of inhibition different in different honey bees?