Why is it important that the initiation of DNA replication is carefully regulated? What is the proposed role of DnaA in this process?

What extra proteins are necessary for lagging-strand synthesis that are not needed in leading-strand synthesis?

Replication in eukaryotes is similar to that of prokaryotes. However initiation is different. Describe how initiation of replication occurs and how it is tied to the cell cycle.

Explain in general terms how DNA replication can occur in a chromatin environment and how epigenetic marks associated with chromatin are conserved during replication.

What are the two general strategies for maintaining the very high degree of fidelity of DNA replication during replication itself?

Following the discovery of DNA polymerase I, what experimental evidence suggested that another enzyme is the primary enzyme of replication?

What are the features of DNA polymerase that ensure the right nucleotides are inserted?

Describe the mechanism of polymerization used by polymerases.

Visceral leishmaniasis has a very high case fatality rate but is difficult to diagnose: bone marrow biopsy, one of the best diagnostic methods, is expensive and is often associated with serious side effects. If you were developing a new diagnostic for this disease, would you be more interested in maximizing sensitivity or specificity? Also, assuming your new test is cheaper and less invasive than biopsy, would you advocate that it be used in conjunction with (ie simultaneously) or prior to (ie sequentially) the invasive diagnostic test? What factors would go into this decision?

One form of male sterility (Ms) in corn is maternally transmitted. Plants of a male sterile line crossed with normal pollen give male-sterile plants. In addition, some lines of corn are known to carry a dominant nuclear restorer allele (Rf-1) that restores pollen fertility in male sterile lines. Another dominant restorer (Rf-2) has been found on a different chromosome. Either or both of the restorer alleles will restore pollen fertility in male sterile lines.

A male-sterile plant is crossed with pollen from a plant homozygous for Rf-1. An F1 plant from this cross is used as the ovule donor, and crossed with pollen from a normal plant (rf-1/ rf-1). What phenotypes are produced by this cross?

the ANSWER is fetile females; 1/2 fertile males; 1/2 sterile males

I was just wondering if you could explain this answer? Thanks!

In studies of human MZ and DZ twin pairs of the same sex who are reared together, the following concordance values are identified for various traits. Based on the values shown, describe the relative importance of genes versus the influence of environmental factors for each trait.

Trait Concordance

MZ DZ

Blood type 100 65

Chicken pox 89 87

Manic depression 67 13

Schizophrenia 72 12

Diabetes 62 15

Cleft lip 51 6

Club foot 40 4

which cell types is most responsible for transplant rejection?

which antibody segment interests with antigens?

what does the CD designation for specific immunity mechanism mean?

GENETICS

Out of 1000 there are 150 that exhibit the recessive bandit eye phenotype which gives them the appearance of wearing a robber mask.

Determine the following

What is p? 0.61

What is q? 0.387

What is the null hypothesis? The values for p and q are not significantly different than the observed frequencies.

You then test the remaining animals and find the following numbers for the genotypes

RR 525    Rr 325 rr 150

What are your new allelic expected allelic frequencies based on this new information (p², 2pq, q²)? <<<Need This Answer >>> The exact values for the new p-squared, 2pq, and q-squared.

What is the X² value ? 0.026

How many degrees of freedom are there? One

What is the p-value? 0.8719

Is the population in HWE? Yes, fail to reject null hypothesis.

Just need the answer for the new P-Squared, 2pq, and q-squared. Thank you.

Topic: Sizing DNA fragments via standard curves using horizontal electrophoresis

Between a low quality ladder (DNA marker) and high quality ladder (Kb ladder), which one produces more accurate estimates on a standard curve? Why?

A. Explain what happened to the buffalo and wildebeest populations in terms of population growth models.

B. What do you expect will happen to these populations going forward?

1-what is the basic structure of a cell 2-what are the three function of the cell membrane 3-what are the three major biological molecules that make up the cell membrane and what are their function 4- what is the purpose of this lab membrane disruption 5- hypothesis

This question is in my plant physiology homework and the assignment is on the electron transport chain.

How is the H⁺ gradient (potential energy) used? What are the products that the proton gradient made? Where in the chloroplast are they made? (3 points)

which two historical figures practiced the use of natural experiments

in 2 paragraphs, please explain how do forensic pathologists and / or anthropologists use skeletal remains?

4. You are studying a new bacterial infection. You have evidence that people are infected by a bacterium; however, you cannot detect any antibodies in the infected individuals to the bacterium. What could be happening?