Hyperparathyroidism is a rare disorder resulting from overactive parathyroid glands (they secrete too much parathyroid hormone,...

Hyperparathyroidism is a rare disorder resulting from overactive parathyroid glands (they secrete too much parathyroid hormone, or PTH). Where does PTH act and what does it do? What do you think happens to the bones of people with this disorder and why? How does this disorder relate to osteoporosis? What other body systems might be affected?

Solutions

Expert Solution

Answer

PTH acts on bones, kidneys and small intestines. PTH indirectly triggers osteoclsts cells in the bones to stimulate bone resorption. It also increases calcium reabsorption in the nephron. In small intestine, it increases absorption of dietary calcium.
In the persons with hyperparathyroidism, the bones become weak and brittle. As PTH resorb bone breakdown the bone mass, excessive PTH levels in blood cause the bone to loose all of its calcium.
As the bone mass is reduced, the bone becomes porous. The bones loose their density and hardness leading to osteoporosis. Bone pain occurs and bone becomes tender. Body posture is altered followed by recurring fractures.
Other systems that might be affected are :
- Urinary system : Due to high blood calcium levels, kidney stones may occur.
- Gastrointestinal system : Nausea, constipation, loss of appetite
- Muscular system : Pain in muscles and muscle weakness.

Sydney Mullin answered 9 months ago

Next > < Previous

Related Solutions

Matching the following term or terms if applicable to pituitary dwarfism: a.) too much parathyroid hormone...

Matching the following term or terms if applicable to pituitary dwarfism: a.) too much parathyroid hormone b.) not enough parathyroid hormone c.) too much thyroid hormone d.) not enough thyroid hormone ab) too many glucocorticoids ac) not enough glucocorticoids ad) too much hGH during childhood ae) not enough hGH during childhood bc) too much hGH during adulthood bd) not enough hGH during adulthood

List the hormones released from the following glands and their action. Some secrete more than 1...

List the hormones released from the following glands and their action. Some secrete more than 1 type of hormone. Pineal gland Thyroid gland Parathyroid glands Thymus Adrenal cortex Adrenal medulla Pancreas

Andre the Giant had a somatotropinoma, which is a tumor that secretes too much hormone on...

Andre the Giant had a somatotropinoma, which is a tumor that secretes too much hormone on it’s own (without the need of outside stimulation). Where would this tumor be located and what hormone is being secreted from this tumor (2 pts)? What hormone normally stimulates somatotroph cells (1 pts)? What happens next in this pathway (continue explaining the pathway as if there wasn’t a tumor) (5 pts)? What negative feedback should be affecting the somatotropinoma (3 pts), and why might...

Which two of the following glands secrete hormones from both endocrine and nervous tissue? Ans choice...

Which two of the following glands secrete hormones from both endocrine and nervous tissue? Ans choice A: adrenals and pituitary B: thyroid and pituitary C: pituitary and pancreas D: pancreas and adrenals

1. A psychologist is working with a patient who suffers from a very rare disorder. Which...

1. A psychologist is working with a patient who suffers from a very rare disorder. Which type of research is the psychologist likely to use? A. Case Study B. Experiment C. Correlation D. Survey 2. Collectivistic cultures value individual achievement above most other aspects of personal behavior. True or False? 3.Replication is the best way to ensure that a research finding is indeed statistically significant. True or False? 4.The fact that newborn babies get more REM sleep than humans at...

Thalassemia is a genetic disorder where affected individuals have red blood cells that produce too much...

Thalassemia is a genetic disorder where affected individuals have red blood cells that produce too much iron. This disease is inherited as an autosomal recessive (tt). However, heterozygous individuals (carriers= Tt) may have some immunity to malaria (similar to sickle cell anaemia). Human blood samples are obtained from a Mediterranean population of 100 people where malaria is endemic. Of these, 50 people are found to be carriers (Tt), and additional 3 people have thalassemia (tt). Use these observed results to...

Cystic fibrosis is an autosomal recessive genetic disorder resulting from the absence of a functional transmembrane...

Cystic fibrosis is an autosomal recessive genetic disorder resulting from the absence of a functional transmembrane conductance regulator (CFTR) protein. A woman whose older sister has a son with the disorder is concerned that she will also have a child with cystic fibrosis. The woman’s husband is healthy but he had a paternal uncle who died of cystic fibrosis as a teenager. A. Based on the information given above, draw a pedigree for the couple and the extended families...

Please rewrite the problem statement for each stakeholder resulting from too many sea lions, the noxious...

Please rewrite the problem statement for each stakeholder resulting from too many sea lions, the noxious smell, and feces/pollution. None of your problem statements address the bad smell, this was the root of the problem. Select three stakeholders from the stakeholder list and Write a problem statement of 2 pages from the perspective of your three stakeholders. stakeholder list 1.Residents 2.visitors- 3. tourist - 4 environmentalists 5-swimmers- 6 preservationists- 7 merchants - 8.researchers please no plagarism it should be original...

Do the Courts have too much power to make policy from the bench? Consider issues such...

Do the Courts have too much power to make policy from the bench? Consider issues such as abortion, equal access to education, the use of religious symbols in public schools, etc. Should decisions on controversial issues like these be made by Courts or by Legislators? Why? Illustrate your answer with your own research.

Do the Courts have too much power to make policy from the bench? Consider issues such...

Subjects