Question

what did yoh learn about GSS

Answer 1

Solution

1. GSS stands for Genome Survey Sequences.
2. It is a branch of bioinformatics and computational biology.
3. GSS are nucleotide sequences similar to EST's that the only difference is that most of them are genomic in origin, NOT of mRNA.

4. GSS are typically generated and submitted to NCBI by labs performing genome sequencing and are used, amongst other things, as a framework for the mapping and sequencing of genome size pieces included in the standard GenBank divisions.

5. Its important to noted that two classes (exon trapped products and gene trapped products) may be derived via a cDNA intermediate.
6. Care should be taken when analyzing sequences from either of these classes, as a splicing event could have occurred and the sequence represented in the record may be interrupted when compared to genomic sequence.
7. The GSS division contains following types of data:

• random "single pass read" genome survey sequences.
• cosmid/BAC/YAC end sequences
• exon trapped genomic sequences
• Alu PCR sequences
• transposon-tagged sequences