Which amino acids are conformationally restricted (rigid) and which is the least?

Solutions

Expert Solution

Proline is conformationally restricted (rigid) and glycine is the least?

Explanation:

Glycine has a hydrogen atom, with a smaller van der Waals radius, instead of a methyl group at the α position. Hence it is least restricted and this is apparent in the Ramachandran plot for glycine for which the allowable area is considerably larger. In contrast, the Ramachandran plot for proline shows only a very limited number of possible combinations of ψ and φ.

gladiator answered 1 year ago

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