Question

1. Different types of bone marrow transplant and pt teaching.

2. You’ve given nitroglycerin, what is your expected therapeutic action on different vital
signs, if applicable?

Answer 1

1.BONE MARROW TRANSPLANT

Bone marrow transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells.

TYPES

There are 3 types of bone marrow transplants. They are

• Autologous bone marrow transplant
• Allogeneic bone marrow transplant
• Umbilical cord blood transplant

AUTOLOGOUS BONE MARROW TRANSPLANT

• Stem cells are removed from you before you receive high dose chemotherapy or radiation treatment.
• The stem cells are stored in a freezer
• After high dose chemotherapy or radiation treatments your stems cells are put back in your body to make normal blood cells. This is called a rescue transplant

ALLOGENEIC BONE MARROW TRANSPLANT

• stem cells are removed from another person called a donor.Most times, the donor's Gene's must at least partly match your Gene's.
• Special tests are done to see if a donor is a good match for you

UMBILICAL CORD BLOOD TRNSPLANT

• This is a type of allogenic transplant
• Stem cells are removed from a newborn baby's umbilical cord right after birth
• The stem cells are frozen and stored until they are needed for a transplant.

2. NITROGLYCERINE

• Nitroglycerin is a prescription drug that is available as the brand name drug nitro stat.
• It is also available as a generic drug

USES

• Nitroglycerin is used to treat angina.
• Angina is a pain or discomfort that happens when part of your heart does not get enough blood.
• It feels like a pressing or squeezing pain.
• It can happen in the chest, neck, arms and lower jaw

MOA

• Nitroglycerin belongs to a class of drugs called vasodilator.
• A class of drug is a group of medications that work in a similar way.
• These drugs are often used to treat similar conditions
• Nitroglycerin works by relaxing the smooth muscle and blood vessels in the body.
• This increases the amount of blood and oxygen that reaches the heart
• In turn the heart doesn't work as hard. This reduces chest pain.

SIDE EFFECTS

COMMON

• headache
• Dizziness
• Weakness
• Fast heart rate
• Nausea
• Vomiting
• Flushing
• Rash

SERIOUS SIDE EFFECTS

• low blood pressure
• Symptoms can include dizziness, fainting, blurry vision, nausea, cold and clammy skin, fast and shallow breathing