During translation, what is the maximum number of tRNAs that can fit into the ribosome at...

During translation, what is the maximum number of tRNAs that can fit into the ribosome at the same time?

I think the answer is 2 but I want to know why

Expert Solution

On ribosomes translation takes place.
The main function of tRNAs is to carry amino acids on to the site of ribosomes for the process of formation of polypeptide chain linking.
The ribosome shows three sites, E site, P site and A site.
The new tRNA enters A site and moves towards p site and exists through E site.
tRNA carries exact amino acid which matches the cocon of mRNA (which sits on ribosome).
Each ribosome shows 2 loaded sites for tRNA on ribosome.
The two loaded sites are A and P of ribosome on which the tRNA with its specific amino acid sits according to the codon of mRNA.
Where as E site on ribosome shows unloaded tRNA without an amino acid. Here this unloaded tRNA exist ribosome. This E site could be seen on ribosome but not binded to mRNA.
Thus A site and P site of ribosome shows loaded tRNA and E site shows empty tRNA.
A site shows AA-tRNA, p site shows peptidyl tRNA and E site shows empty tRNA.
Thus at the same time two tRNA molecules can occupy the ribosome.

gladiator answered 2 years ago

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