lipooxygenase pathway

Expert Solution

Lipooxygenase pathway...

Phospholipids present in cell membrane with the help of Phospholipase it is converted into Arachidonic acid..

Phospholipase is inhibited by Corticosteroids...

This Arachidonic acid is converted into 5-HPETE with the help of Lipooxygenase enzyme..

Lipooxygenase enzyme is inhibited by zileuton..

This 5-HPETE is converted into LTA4 with the help of Lipooxygenase..

HPETE means hydroperoxy eicosatetraenoic acid..

This LTA4 has two pathways

a. With the help of hydrolase enzyme it is converted to LTB4.

b. With the help of LTC4 synthase it is converted to LTC4..

This LTC4 is converted to LTD4 with the help of Transferase enzyme..

LTD4 is converted into LTE4 with the help of peptidase enzyme...

Function of these Leucotrines are

1. LTB4- helps in neutrophils chemotaxis..

2. LTC4, LTD4, LTE4- causes Bronchoconstriction.

I hope by the above description u got your answer.. if u have any questions you can ask in comment section..

Nightingale answered 2 years ago

Complement pathways _ Explain how classical pathway, Alternative pathway, lectin pathway and terminal pathway are activated...

Complement pathways _ Explain how classical pathway, Alternative pathway, lectin pathway and terminal pathway are activated to destroy bacterial cells?

Explain how classical pathway, alternative pathway, lectin pathway and terminal pathway destroy bacterial cells in detail.

The intrinsic pathway of coagulation is activated by the The intrinsic pathway of coagulation is activated...

The intrinsic pathway of coagulation is activated by the The intrinsic pathway of coagulation is activated by the release of heparin from the liver. sticking of platelets to damaged tissue. activation of proenzymes exposed to collagen. release of tissue factor (Factor III) by damaged endothelium. conversion of prothrombin to thrombin.

Describe the pathway that transmits pain stimuli to the brain and the analgesic pathway that will...

Describe the pathway that transmits pain stimuli to the brain and the analgesic pathway that will lessen pain sensitivity.

A descrptive pathway of Heat Shock Protein 104 and A pathway of the Gene knockout in...

A descrptive pathway of Heat Shock Protein 104 and A pathway of the Gene knockout in yeast. ( on a biological level )

9. Which G protein signaling pathway elevates calcium? A. What is the pathway for elevation of...

9. Which G protein signaling pathway elevates calcium? A. What is the pathway for elevation of calcium? B. What is Calmodulin. How is it relevant to calcium elevation? C. What is myosin light chain kinase? (1)What does it do? (2) How is it activated? (3) What is its effect on smooth muscle?

Ascending afferents from both the medial lemniscal pathway and the spinothalamic pathway of the spinal cord...

Ascending afferents from both the medial lemniscal pathway and the spinothalamic pathway of the spinal cord synapse in the ventral posterior nucleus of the thalamus (VPN). The VPN has two parts: the medial VPN and the lateral VPN. (a) What somatosensory afferents synapse in each of these two areas and (b) to which 3 areas do neurons from the VPN project?

Question

lipooxygenase pathway

Solutions

Expert Solution

Related Solutions