In: Anatomy and Physiology
The intrinsic pathway of coagulation is activated by the
The intrinsic pathway of coagulation is activated by the
| release of heparin from the liver. |
| sticking of platelets to damaged tissue. |
| activation of proenzymes exposed to collagen. |
| release of tissue factor (Factor III) by damaged endothelium. |
| conversion of prothrombin to thrombin. |
activation of proenzymes exposed to collagen.
The intrinsic pathway is activated through exposed endothelial collagen. Exposure to endothelial collagen leads to activation of Factor XII which becomes Factor XII A