In: Anatomy and Physiology
The intrinsic pathway of coagulation is activated by the
The intrinsic pathway of coagulation is activated by the
release of heparin from the liver. |
sticking of platelets to damaged tissue. |
activation of proenzymes exposed to collagen. |
release of tissue factor (Factor III) by damaged endothelium. |
conversion of prothrombin to thrombin. |
activation of proenzymes exposed to collagen.
The intrinsic pathway is activated through exposed endothelial collagen. Exposure to endothelial collagen leads to activation of Factor XII which becomes Factor XII A