In: Anatomy and Physiology
The intrinsic pathway of coagulation is activated by the
The intrinsic pathway of coagulation is activated by the
| release of heparin from the liver. | 
| sticking of platelets to damaged tissue. | 
| activation of proenzymes exposed to collagen. | 
| release of tissue factor (Factor III) by damaged endothelium. | 
| conversion of prothrombin to thrombin. | 
activation of proenzymes exposed to collagen.
The intrinsic pathway is activated through exposed endothelial collagen. Exposure to endothelial collagen leads to activation of Factor XII which becomes Factor XII A