Question

In: Biology

The bending of the neural plate involves all of the following, except? a. Formation of hinge...

The bending of the neural plate involves all of the following, except?

a. Formation of hinge regions

b. Cell wedging/cell shape changes

c. High BMP signaling

d. Medial forces from the surface ectoderm

Solutions

Expert Solution

ANSWER : The correct alternative is (c) High BMP signalling.

REASON- . It has been seen some moleules like noggin, chordin, follistatin(in amphibians) inhibit the BMP signalling i.e more specifically block the Bone Morphogenic protein -4 (BMP-4) which induces neural tube forrmation,supressing the epidermal exprression.

All the the other three alternatives are events ocuuring in the process of neural tube bending.

(a) Formation of hinge regions- The events of bending of neural plate involves the formation of hinges , whereby the midline of the neural plate is called median hinge point i.e MHP.

(b) Cell wedging/Cell shape changes- The cells present in median hinge point i.e MHP will begin to change shape , they will in turn decrease in height and become wedge-shaped. This process is called cell wedging.

(c) Medial forces from the surface of ectoderm- The extrinsic medial forces pushes the surface ectoderm towards the midline , so that the bending of neural tube occurs.


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