Question

In: Biology

i. Type II hypersensitivity or antitotoxic reaction of the antibody involves the following EXCEPT A. is...

i. Type II hypersensitivity or antitotoxic reaction of the antibody involves the following EXCEPT

A. is mediated by antibodies such as IgG and IgM.

B. is a toxicotoxicity mediated by complement

C. Causes antibody-mediated body cell dysfunction

D. The body's cytotoxicity is mediated by cells such as antibody-dependent macrophages

E. The production of too many antibodies against the bacterial cells that make up the immune complex.

ii. The function of eosinophils in Type I hypersensitivity is
A. neutralizes vasoactive factors from cell poles.
B. avoid insects start biting.
C. polar cell degeneration cells.
D. The release of prostaglandins.
E. destroy the larval worm.

Solutions

Expert Solution

Answer 1--A --wrong

type 1 hypersensitivity reaction also called as anaphylatic reaction it is antibody mediated reaction

example --bronchial asthma ,good and pollen allergy allergic rhinitis etc

Pathogenesis-- when antigen enter in body it is revognised by antigen presenting cells

And antigen presenting cell digest it and represent on their surface it is stimulate T helper 2

T helper release interleukin 4 which stimulate release of IgE antibody

and also release interleukin 5 which recruitment of eosinophils

On first expisure mast cell sensitize for the antigen

further exposure..polymerisation and degranulation of mast cell

Occur early phase reaction--due to preformed mediators
, histamin which cause vasodilation and brochial muscle contraction

On late phase reaction--cytokine leukokine chemokine release and causes tissue distruction and epithelial damage


Answer 2-- eosinophil stimulate to release of prostaglandin histamin chemokine leukotriens


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