In: Biology
What are two examples of negative consequences that can occur from the action of transposons, and explain why those events are potentially bad?
Negative consequences that can occur from the action of
transposons are explained below and those events are potentially
bad because :
1) As transposition process inactivate genes because expression of
gene is disrupted by insertion of the transposable element. A
transposon inserts itself into a functional gene, it will probably
damage it. If it is nserted into exons, then genes it codes for
will damage and required protein will not form. It can destroy or
alter the gene's activity.
Example to explain why it is potentially bad. r allele (rugosus) of
the gene encoding a starch branching enzyme in peas will be
nonfunctional due to insertion of a transposable element.
2) Transposition can activate nearby genes by bringing an enhancer
of transcription close to a gene that stimulate its expression. If
target gene is not usually expressed in a certain cell type and
activation of that gene by transposition will lead to cancer. For
example, activation of a proto-oncogene causes cell to become
cancerous.