Question

In: Chemistry

Brucine is a bitter alkaloid closely related to strychnine. It occurs in several plant species, the...

Brucine is a bitter alkaloid closely related to strychnine. It occurs in several plant species, the most well known being the Strychnos nux-vomica tree, found in South-East Asia. While brucine is related to strychnine, it is not as poisonous. Nevertheless, a human consuming over 2 milligrams of pure brucine will almost certainly suffer symptoms resembling strychnine poisoning. For medicinal purposes, brucine is primarily used in the regulation of high blood pressure and other comparatively benign cardiac ailments. Brucine (C23H26N2O4 ; mm = 394.46 g/mol; Kb = 1.9 x 10-6) and strychnine (C21H22N2O2; mm = 334.41 g/mol; Kb = 1.8 x 10-6) form crystalline solids upon reaction with hydrochloric acid (stomach acid). Both brucinium chloride (C23H27N2O4+ Cl-; mm = 430.92 g/mol) and strychninium chloride (C21H23N2O2+ Cl-; mm = 370.87 g/mol) are very soluble.

What is the molar concentration (M) of a solution of brucinium chloride that has a pH = 5.77?

Solutions

Expert Solution

Ans. Given, Kb of brucine = 1.9 x 10-6

Now, pKb = - log (Kb) = -log (1.9 x 10-6) = 5.72

# pOH of solution = 14.00 – pH = 14.00 - 5.77 = 8.23

# A solution of Brucine and brucinium chloride (when HCl is added to pure solution of Brucine) for a buffer of weak base and its conjugate acid.

Using Henderson-Hasselbalch equation for base-

            pOH = pKb + log ([BH+] / [B])

            Where,

                        B = Base = Brucine

                        BH+ = Conjugate acid = Brucinium chloride (BH+Cl-)

            Putting the values in above equation-

            Or, 5.77 = 5.72 + log ([BH+] / [B])

            Or, 5.77 – 5.72 = log ([BH+] / [B])

            Or, ([BH+] / [B]) = antilog (0.05)

            Or, ([BH+] / [B]) = 1.122

            Or, [BH+] = 1.122 [B]

# To calculate molar concertation of BH+, the unknown [B] in above term “[BH+] = 1.122 [B]” must be provided.

# Please multiply [B] with 1.122 to get [BH+], if [B] in known. In this question, [B] is NOT known. Or, there is NOT information available to calculate [B].


Related Solutions

Suppose a hypothetical bird species (species Gamma) differs from a closely related bird species (species Delta)...
Suppose a hypothetical bird species (species Gamma) differs from a closely related bird species (species Delta) in several ways, including being much more aggressive. How would you set up an experiment to determine if environment or genetics plays a larger role in the Gamma bird species aggression? You would relocate some adult Gamma birds to a Delta bird habitat and some adult Delta birds to a Gamma habitat and compare the aggressive behaviors in their new environment to their aggressive...
Two closely related species of mushrooms (I and H) are difficult to identify without the aid...
Two closely related species of mushrooms (I and H) are difficult to identify without the aid of a microscope. One method used in the field to separate the two species is to note the presence or absence of a ring on the stalk of the plant. Ninety percent of species I and 20% of species II have the ring. It is also known that in the particular area where the mushrooms are being studied, 70% of them are species I....
Problem III. A very large population of a flowering plant species occurs in a lowland meadow....
Problem III. A very large population of a flowering plant species occurs in a lowland meadow. A small population of the same species occurs on a remote mountainous region more than 200 km away. You collect seeds and raise several plants from each population in the same greenhouse. You measure flower size on plants of each population and find the following: Mountainous region: mean flower diameter = 1.2 cm Lowland meadow: mean flower diameter = 5.2 cm Now on a...
The plant alkaloid, Vinblastine, is used to treat a number of types of cancer. It causes...
The plant alkaloid, Vinblastine, is used to treat a number of types of cancer. It causes depolymerization and destabilization of microtubules. In which of the following cell cycle stages, would treated human cells be most likely arrested or stopped? options: S M G2 G1
The plant alkaloid, Vinblastine, is used to treat a number of types of cancer. It causes...
The plant alkaloid, Vinblastine, is used to treat a number of types of cancer. It causes depolymerization and destabilization of microtubules. In which of the following cell cycle stages, would treated human cells be most likely arrested or stopped? options: S M G2 G1
1) Microbial growth occurs in the precense or abcense of oxygen which is related to several...
1) Microbial growth occurs in the precense or abcense of oxygen which is related to several factors. Identify those factors. 2) Explain one way to perform the Oxidase test.
Which of the following responses is most closely related to the statements.
Which of the following responses is most closely related to the statements.  Known or postulated etiology Associated with decreased surfactant production A yet unknown hereditary link Unknown etiology Associated with low birth weight and pre-term birth. Associated with Atelectasis. A. Respiratory Distress Syndrome (RDS)  B. Sudden Infant Death Syndrome (SIDS)  C. Both of the responses D. None of the responses
1. Who is most closely related to SUPPLY-SIDE economics?
1. Who is most closely related to SUPPLY-SIDE economics?Robert LucasMilton FriedmanAlan BlinderJohn Maynard KeynesArthur Laffer2. Who is most closely related to NEW CLASSICAL economics?Alan BlinderArthur LafferRobert LucasMilton FriedmanJohn Maynard Keynes3. Who is most closely related to NEW KEYNESIAN economics?Robert LucasAlan BlinderMilton FriedmanArthur LafferDavid Ricardo4. Who is most closely associated with the notion of ABSOLUTE ADVANTAGE?Robert LucasAdam SmithMilton FriedmanDavid RicardoAlan Blinder5. Who is most closely associated with the notion of COMPARATIVE ADVANTAGE?Group of answer choicesDavid RicardoRobert LucasAdam SmithMilton FriedmanAlan Blinder
Size of the firm is closely related with competitiveness of the firm, particularly in a global...
Size of the firm is closely related with competitiveness of the firm, particularly in a global market. Using the concept of minimum efficient scale (MES) at long run average cost curve explain why firms in some industries can have market power to set price strategically than firms in other industries.
Size of the firm is closely related with competitiveness of the firm, particularly in a global...
Size of the firm is closely related with competitiveness of the firm, particularly in a global market. Using the concept of minimum efficient scale (MES) at long run average cost curve explain why firms in some industries can have market power to set price strategically than firms in other industries.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT