Question

In: Anatomy and Physiology

1) Describe the main adverse effects of H1 an H2 receptor antagonists. 2) Describe the main...

1) Describe the main adverse effects of H1 an H2 receptor antagonists.

2) Describe the main contraindications of H1 an H2 receptor antagonists.

3) Describe the main therapeutic uses of H1 and H2 receptor antagonists.

Solutions

Expert Solution

Main adverse effects of H1receptor antagonists

Drowsiness, dizziness, tinnitus, blurred vision, euphoria, incoordination, anxiety, increased appetite leading to weight gain, insomnia, tremor, nausea and vomiting, constipation, diarrhea, dry mouth, and dry cough, stomach upset etc.

Main adverse effect s of H2 receptor antagonist

Common adverse effects includes constipation, diarrhea, difficulty sleeping, dry mouth, dry skin, headaches, ringing in the ears, runny nose etc.

Contraindications of H1 receptor antagonist

Hypersensitivity to the drugs or other phenobarbital is a contraindication.

First generation H1 receptor antagonist is contraindicated in angle- closure glaucoma, pyloric stenosis.

Pregnancy and childhood.

Contraindications of H2 receptor antagonist

No absolute contraindications.

Pregnancy and childhood.

Patient with swallowing difficulty, vomitus with blood, bloody or black stools.

Therapeutic uses of H1 receptor antagonist

It block the action of histamine at the H1 receptor, helping to releave allergic reactions.

Medical uses includes allergic rhinitis, congunctivitis, skin conditions, rhinorrhea,urticaria etc.

Therapeutic uses of H2 receptor antagonist

H2-receptor antagonists are used to treat duodenal ulcers .They are also used to treat gastric ulcers and for some conditions, such as Zollinger-Ellison disease, in which the stomach produces too much acid.


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