Fact:Without thiamine (vitamin B1), the body cannot convert pyruvate into acetyl-CoA, or use 6 of the...

Fact:Without thiamine (vitamin B1), the body cannot convert pyruvate into acetyl-CoA, or use 6 of the 22 amino acids in the Krebs cycle. Explain in detail why a person with a thiamine deficiency would have a reduced physical work capacity.

Detailed answer please!

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Expert Solution

Without thiamine (vitamin B1), the body cannot convert pyruvate into acetyl-CoA, or use 6 of the 22 amino acids in the Krebs cycle. thiamine deficiency would have a reduced physical work capacity because don't get enough thiamine, you may first have nausea, vomiting, loss of appetite, fatigue and difficulty concentrating. ... If thiamine deficiency is severe, serious problems can result including loss of hearing, permanent nerve damage, coma, permanent brain damage, heart damage, liver damage, and death.

Thiamin (vitamin B1) helps the body's cells change carbohydrates into energy. The main role of carbohydrates is to provide energy for the body, especially the brain and nervous system. Thiamin also plays a role in muscle contraction and conduction of nerve signals. Thiamin is essential for the metabolism of pyruvate.

Energy is needed to work for that thiamin is essential so thiamine deficiency would have a reduced physical work capacity.

Sydney Mullin answered 10 months ago

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