Question

Condition : Turner Syndrome (45, XO) in XO individual (compare with typical XX)

compare the developent with the development of an individual of the same sex chromosome set, but without any of the mutations that caused the condition

Answer 1

Turners syndrome is a conditional seen in females. It occurs due to loss of one X chromosome. As a result, the chromosome complement in somatic cells is 45,XO. The karyotype of an individual is 45,X.

Comparison between XO (Turner's female) with XX (normal female) Development -

Turner's female -

1)Ovarian(gonadal) dysgenesis-

It is associated with absence of gonads(ovaries) and karyotype pattern is XO i.e only one sex chromosome is present.

2)Delayed puberty-

Diminished sexual development of female type, short stature and webbing of the neck(due to delayed maturation of lymphatics).

3)Amenorrhea(non-appearance of menstruation) due to gonadal dysgenesis.

4)other features-broad shied like chest with pinpoint nipples, low-set ears, infantile external genitalia.

Normal female(XX) -

1) Normal gonads(presence of pair of ovaries in a female reproductive tract).

2)Puberty(period of growth and maturation) attained at normal age i.e in between 9 to 14 years.

3)Normal periodic menstruation/menstrual cycle i.e 28 days.

4)Normal stature, neck, ears and external genitalia.