Question

condition swyer syndrome .

Compare the development of the individual with the condition you chose in question #1 with the development of an individual of the same sex chromosome set, but without any of the mutations that caused the condition

Answer 1

Generally, the karyotype of a female is 46, XX and that of the male is 46, XY. The gonads in each female and male grow according to the chromosomal organisation of XX and XY. The individual with normal autosomal and sex chromosomes have normal hormonal functioning and normal development of external genitalia.

The individual that has the Swyer syndrome has hypogonadism. The individual with this syndrome has the chromosome number as 46,XY. This means that the individual is female externally but does not have any functional gonads. The developmental stages are :

• Sexual differentiation in the fetus with XY chromosomes
• The SRY genes are responsible for the secretion of other hormones and genes that are responsible for the development of the sexual characters and gonads.
• Mutation in the SRY genes cause the syndrome
• The mutation inhibits secretion of antimullerian hormones and no tetsosterone is secreted and thus there is development of the female organs.