Question

In: Anatomy and Physiology

Are autocrine and paracrine types of hormones or just a delivery mechanism by which they act?

Are autocrine and paracrine types of hormones or just a delivery mechanism by which they act?

Solutions

Expert Solution

Autocrine and paracrine are both delivery mechanism and hormone effects. Autocrine: mode of hormone action to which hormons bind to receptors on to the cell and affects the cell that produces it. e.g. growth factors that stimulate cell division. Paracrine: describes hormone action where hormones are released from cells and bind to receptor on nearby cells and affects their function.

  • Paracrine signaling acts on nearby cells, endocrine signaling uses the circulatory system to transport ligands, and autocrine signaling acts on the signaling cell.
  • Autocrine signaling: a cell targets itself, releasing a signal that can bind to receptors on its own surface.
  • paracrine actions of hormones are provided by the ovaries and testes.
  • Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell.

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