Eicosanoids are paracrine hormones that have a variety of dramatic effects on vertebrate tissues. There are...

Eicosanoids are paracrine hormones that have a variety of dramatic effects on vertebrate tissues. There are three classes of eicosanoids. Define each of these classes and elaborate on their functions. What are NSAIDs and what is the basis behind NSAIDs function?

Three classes of eicosanoids: prostaglandins, thromboxanes, and leukotrienes.

Solutions

Expert Solution

Eicosanoids are 20 C compounds derived from Arachidonic acid.

1. Prostaglandins: Present in almost all tissues. Most potent biological active substances because at very low concentration, it cause smooth muscle contraction. Prostacyclinn(PGI2) has a major effect of vasodilation and inhibit platelets aggregation.

2. Thromboxanes: It is produced by platelets. Its main effect is vasoconstriction and platelets aggregation.

3. Leukotrienes: Most potent chemotactic agent (factor attracting cells to the inflammatory cells). The slow reacting substance of anaphylaxis ( SRS- A) contains LTC4, LTD4 ,etc. It cause smooth muscle contraction,bronchioles contraction, increases capillary permeability, activate leucocytes and produce vasoconstriction. Leukotrienes has major role in asthma.

gladiator answered 2 years ago

Next > < Previous

Related Solutions

Are autocrine and paracrine types of hormones or just a delivery mechanism by which they act?

1. How do polypeptides have the following types of effects: autocrine, paracrine, and endocrine 2. If...

1. How do polypeptides have the following types of effects: autocrine, paracrine, and endocrine 2. If you experimentally increase the concentration of Na+ outside a cell while maintaing other ion concentrations as they were, what would happen to the cell's membrane potential? Can you please exaplin why? a - membrane potential would increase b - membrane potential would decrease c - membrane potential would be unaffected d - depends on thermodynamy potential

Briefly describe 10 specific effects that hormones have on the body.

Know all of the hormones that have their effects on the kidneys, and what those specific...

Know all of the hormones that have their effects on the kidneys, and what those specific effects are, and know about the hormones and enzyme (Renin) released by the kidneys and their target tissues and effects at the various tissues.

____ are steroid hormones which have masculinizing effects Mineralocorticoids Glucocorticoids Water- soluble hormones Adrenalins andgrogens All...

____ are steroid hormones which have masculinizing effects Mineralocorticoids Glucocorticoids Water- soluble hormones Adrenalins andgrogens All of the following are hormones of the anterior pituitary EXCEPT ____ Thyroid stimulating hormones Oxytocin Follicle stimulating hormone Luteinizing hormone Adrenocorticotropic hormone An enlarged thyroid gland, increased heart rate and blood pressure, weight loss, and agitation/nervousness could be symptoms of ____ Acromegaly Hypothyroidism Hyperthyroidism Hypoglycemia hyperglycemia ____causes body cells to divide so that tissues are maintained/ repaired during adulthood Parathyroid hormone Aldosterone Cortisol Melatonin...

List the target tissues and major function for each of the following hormones: a. thyroxine b....

List the target tissues and major function for each of the following hormones: a. thyroxine b. prolactin c. testosterone d. antidiuretic hormone e. oxytocin f. growth hormone g. aldosterone h. cortisol i. epinephrine j. luteinizing hormone

Describe the anterior pituitary hormones and their physiological effects.

Show effects of certain hormones on urine output

Endocrinology: how do the two types of hormones work to activity/ inhibit target cells? Vertebrate endocrinology:...

Endocrinology: how do the two types of hormones work to activity/ inhibit target cells? Vertebrate endocrinology: which hormone comes from which gland and what are their targets? What are the release mechanisms of the P. pituitary versus the A. pituitary? How do various human hormones regulate the reproductive abilities of males and females, including fetal, puberty, daily and monthly cycles, and of course pregnancy?

Describe “The intracellular superfamily of hormones and how they mediate their effects”

Subjects