What 2 antagonistic hormones in the hypothalamus regulate growth hormone secretion?

Expert Solution

Growth hormone also called as human growth hormone (HGH) is a peptide hormone secreted by the somatotropic cells of the anterior pituitary gland. It regulates the overall growth and maintenance of body tissues.

The synthesis of growth hormone is regulated by hypothalamus. Hypothalamus has neurosecretory nuclei which secretes growth hormone releasing hormone (GHRH) also known as somatocrinin and growth hormone inhibiting hormone (GHIH) also known as somatostatin. These two hormones are produced by hypothalamus and transported to the pituitary gland where they regulate the secretion of growth hormone by acting as antagonist to each other. Growth hormone releasing hormone(GHRH) stimulates the secretion of growth hormone from the pituitary gland and growth hormone inhibiting hormone(GHIH) inhibits the secretion of growth hormone.

Growth hormone secretion and release in the pituitary gland from the somatotropic cells of anterior pituitary is regulated by the signals of these two antagonistic hormones (growth hormone releasing hormone and growth hormone inhibiting hormone) from hypothalamus.

Sydney Mullin answered 1 year ago

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