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How is the release of oxygen from hemoglobin achieved in the blood? Be sure to define...

How is the release of oxygen from hemoglobin achieved in the blood? Be sure to define and discuss the Bohr effect

Solutions

Expert Solution

• Almost 97% oxygen in blood is transported by hemoglobin.
• Hemoglobin binds to oxygen and converted into oxyhemoglobin.
• Oxygenated blood supplies oxygen to various tissues of body.
• When blood reaches to tissue level then oxygen dissociates from oxyhemoglobin and oxygen is released to tissues.

Bohr effect :-
• This effect explains effect of carbon dioxide on oxygen dissociation.
• At tissue level, carbon dioxide concentration is higher. This carbon dioxide combines with water and forms carbonic acid.
• This carbonic acid decreases the pH of blood. On lower pH, affinity of hemoglobin towards oxygen is decreased and oxygen is released from oxyhemoglobin.
Hence, release of oxygen is occurred.

Defination of bohr effect -
" Decrease in oxygen affinity of hemoglobin in response to decreased blood pH is result of increased carbon dioxide concentration in blood."


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