Topic 9: Oxygen-hemoglobin dissociation
curve
Define what the oxygen hemoglobin dissociation curve is
and describe why it is physiologically important. explain the
significance of the sigmoidal shape, including the physiological
significance of the plateau and step portions, and the relationship
between oxygen loading/unloading with changes to po2
Give an example of a situation/condition that would
result in a right shift of the oxygen hemoglobin dissociation
curve. explain what causes the shift and relate it to oxygen
binding affinity, loading-unloading of...
If you plot an oxygen-hemoglobin saturation curve for a mammal
and want to add a curve for myoglobin, you would have to put place
it _________ the o2-Hb curve. This reflects myoglobin's affinity
for oxygen.
A. over; similiar B. to the left of; increased C. To the right
of; decreased D. to the right of; increased
In mammals, the major control of ventilation is blood_______and
in fish, the major control of ventilation is blood________.
A. Co2 level; oxygen level B....
Draw an oxygen saturation curve for hemoglobin (pressure of O2
versus saturation (y)) with physiological levels of CO2 and 2,3-BPG
at biological pH. Now using arrows to indicate which direction it
moves, draw the shift in this curve when:
a) There is a decrease in CO2
b) There is an increase in 2,3-BPG
c) There is an increase in pH
d) Hemoglobin experiences a loss of quaternary structure (breaks
up into monomers)
18. Regarding the oxygen-hemoglobin dissociation curve, a
patient suffering from a fever would have a hemoglobin saturation
curve shifted to the of a normal hemoglobin curve as an increase in
temperature causes affinity for oxygen. a. left // higher b. left
// lower c. right // higher. d. right // lower. e. None of
these—temperature does not affect hemoglobin’s affinity for
oxygen.
Given knowledge of local regulation of gas transport, the
oxygen-hemoglobin saturation curve, and neural control of
respiration, give at least five reasons why exercising muscles that
use more oxygen and produce more carbon dioxide, lactic acid and
heat would have more oxygen delivered to them.
53-1/Acidic pH shifts the O2 -hemoglobin dissociation curve to the
right. What will the result of this shift be?
Select one:
_ a. More H+ will be unloaded in the pulmonary capillaries
I
b. Less H+ will bind to hemoglobin than O2
C. Less CO2 will be unloaded in the systemic capillaries
d. More O2 will be unloaded in the systemic capillaries
2/Which of the following activates chymotrypsinogen in
pancreatic juice?
Select one:
_ a. Enterokinase _
b. Trypsin
C....