Question

I need a response to this discussion please, It should be two paragraphs.

According to the researchers, melatonin has many uses, common being insomnia, and jet lag. It is also used for heart disease, symptoms of menopause, benzodiazepine withdrawal in the elderly, breast and prostate cancer prevention and treatment, fibromyalgia, IBS, epilepsy, pulmonary sarcoidosis, and to increase chances of pregnancy in women with polycystic ovarian syndrome. Topical melatonin is used to prevent and treat sunburn. In a study done by the National Natural Science Foundation of China, melatonin was given to severely burnt rats with less than 60% kidney function. After administration, the glomerular filtration rate was drastically improved and creatinine and BUN levels dropped. It also reduced inflammatory response by inhibiting inflammatory cytokines and increasing the action of inflammation reducing cytokines. In their study they concluded that melatonin activates sirtuin 1, a nicotinamide adenosine dinucleotide dependent deacetylase that regulates hepatic lipid homeostasis, which has a protective and therapeutic effect on the kidneys. They believe this serves as evidence that melatonin has the potential to improve renal function and prevent acute kidney injury in burn victims (Bai et al., 2016). recommended dosage for insomnia ranges from 0.5 to 5mg. it should be taken 1 hour prior to bedtime. For other indications, there are no widespread recommended dosage amounts for melatonin. The doctor decides on the dosage based on the individual needs of the patient, usually as a part of multimodal treatment. Side effects of melatonin may include nightmares and a hangover effect. A lower dose can prevent this. Probiotics is largely used by alot of people but has not been approved by the Food and Drug Board for its medical uses, but its recommended by medical professionals for people with digestive problems. Its recommend to be used as a complimentary treatment. It is not approved by the FDA, but it helps for treatment and prevention of diarrhea and irritable bowel syndrome. It may play a role in aiding digestion for patients suffering from some digestive diseases, including irritable bowel syndrome, inflammatory bowel disease, antibiotic-associated diarrhea, and Clostridium difficile-associated diarrhea (Stevens, 2016). The recommended dosage is 250 mg – 500 mg two to four times a day. The properties of probiotics may help strengthen homeostasis and thus reduce side effects associated with cancer and other disease treatments (Mego, Holec, Drgona, & Hainova, 2013). Probiotics alters the properties of gut microorganisms, which range from their growth to their metabolism and use of nutrients. These alterations appear to influence glucose and fat metabolism in the host (Arora, Singh, & Sharma, 2013). Side effects are bloating, constipation, and flatulence. Antifungal medications may decrease effectiveness of probiotics, but there is limited data to support contraindications of this supplement. Since, this is not approved by the FDA,nursing intervention is to educate patients and other groups to read package labels carefully to ensure safe and efficacious use.

Answer 1

Melatonin plays major roles in our body health prevention. It is being produces naturally in our body specially at the time of sleeping hours. It is also used for treating insomnia, heart diseases as well as many other chronic disease. A sound sleep could reduce the risk of other diseases. But due to various factors people are facing insomnia. The melatonin is also used in the women suffering from polycystic ovary syndrome. So, there are many benefits of the melatonin. It is also used topically on the skin in the case of the sunburn. Melatonin plays various roles in our daily body functioning. It reduces the body inflammation, it also reduces the risk of kidney dysfunction risk etc.

Probiotics is a most useful ingredient for the stomach and digestive system.In many of the research, it has been found that it could reduce the bowel irritability symptoms. It may play a role in aiding digestion for patients suffering from some digestive diseases, including irritable bowel syndrome, inflammatory bowel disease, antibiotic-associated diarrhea, and Clostridium difficile-associated diarrhea. Sometimes antifungal drug may decrease the efficacy of the probiotics.