In: Anatomy and Physiology
JT is a 20 year old female on a continuous infusion of an antibiotic. The total dose that will be given is 1500 mg over 24 hours. The volume of distribution is 69 L and the drug half life is 6.7 hours. What is the plasma drug concentration if a blood sample is taken 29 hours after the infusion began? Note: Please provide your answer in units of mg/L.
A= C. Vd
here A= amount of the drug in the body
C = plasma concentration
Vd = volume of distribution of drug
1500mg= C. 69L
C= 1500mg/69L
C= 21.73mg/L
therefore plasma drug concentration in blood = 21.7mg/L