Question

Write the article summary "A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives" by Yoav Ben-Shlomo, Diana Kuh.

what is the article about? some key points of the article?

how this article related to our outside of the world?

Answer 1

A review on life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspective

*It is an approach for learning the intra and inter-generation gap .It also involves the study of long-term effects of physical , social vulnerability on health and also diseases and risk during different time periods such as gestation, childhood, adolescence, young adulthood, and later adulthood .

*It also involves the study of risk over the life course, critical periods of health and development.

* The exposures which occur during to he critical time periods have unrepairable impacts on the temporal ordering and interrelationships of exposures, and biological, behavioral, and psychosocial behaviour

Key points

1)Conceptual Models in Life Course Epidemiology-

Earlier by convention the chronic disease cohort studies enrol subjects in middle age and follow them up for future disease end-points. The chance of developing disease is then associated with the baseline of exposures or changes in exposure.

2)Explaining the concept of critical in critical period

This concept basically recognizes the importance of effect modifiers in our later life. During the course of study stopping the additive effect will have health benefits but residual damage will remain with us

3) Explanation of variation of determinants of health in Individual by considering inter and intra genartion gap and population .

4) Introduction of a life course approach presents major challenges for both the design and analysis of epidemiological studies.

The impact of article to outside world includes

*The assumption that disproportion in health today, either between or within countries are caused due to differences in critical situation of life is not viable for a range of serious diseases that appears due poor socioeconomic circumstances .

The future value of this approach in life will depend for its success on explain new mechanisms and pathway of disease .